Nov. 16, 2010
Applications

Confocal Nanoscopy Goes Multicolor

Discovering Cellular Morphology Beyond the Diffraction Limit

  • Fig. 1: Nuclear structures visualized with Chromeo 494 (green) and Atto 647N (red). Sample: courtesy of Dr. L. Schermelleh, LMU Biozentrum, Munich, GermanyFig. 1: Nuclear structures visualized with Chromeo 494 (green) and Atto 647N (red). Sample: courtesy of Dr. L. Schermelleh, LMU Biozentrum, Munich, Germany

Scientists long to understand the architecture of life. They want to learn how biological structures are arranged in respect to one another. Do they co-localize within or are they excluded from the same superstructure? Does localization follow a special pattern and how does the overall arrangement reflect the biological function? Multicolor superresolution imaging allows these fundamental questions to be addressed by far-field fluorescence microscopy in unprecedented detail.

Authors

Contact

Leica Microsystems GmbH
Am Friedensplatz 3
68165 Mannheim
Germany
Phone: +49 621 7028 2801
Telefax: +49 621 7028 8011

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