Non-Invasive Tomography of Living Cells
Non-Invasive Holo-Tomographic System for Live Cell Nanoscopy
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Since the discovery of the cell as the basis of all life on earth, scientists became aware that unveiling the microcosm inside cells would open a objective amount of possibilities. However, cell’s small dimensions and transparent nature made this mission very challenging. The most used approach to address these issues is to combine conventional microscopy with chemical markers to increase contrast. Most of these techniques are invasive to the cells with risk of damaging and results falsification. This article presents a novel non-invasive imaging approach for quantitative analysis and differentiation of cell components in 3D .
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 Y. Cotte et al.: Marker-free Phase Nanoscopy, Nature Photonics, vol. 7, pp.113-117 (2013)
 Y. Cotte et al.: Microscopy image resolution improvement by deconvolution of complex fields, Opt. Express, vol 18, n°1, p. 19462-19478 (2010)
 L. Pollaro et al.: Digital Staining: Microscopy of Live Cells without Invasive Chemicals, Microscopy Today, vol 23, n°4, pp. 12-17 (2015)
 E. Wolf: Principles and development of diffraction tomography, Trends in Optics, vol. 3, pp.
83–110 (Academic, 1996)
Bastien Della Piazza1
1Nanolive SA, Ecublens, Switzerland