- Date: Jan. 21 - Jan. 26, 2018
- Place: Les Houches, France
- Website: http://www.e-smi.eu
New in vitro and in vivo applications of physics and mathematics for the imaging of metabolism at the cellular, organ and organism levels will be discussed.
For decades shelved as old biochemistry for undergraduates, the central position of metabolism in biology recently revived. Metabolism is central in brain activity and firing of neurons; in heart and muscle physiology; cancer is a metabolic glutton; accumulation of metabolic waste leads to atheroma; and diabetes, obesity and other metabolic disorders are the plague of modern medicine. Novel metabolites emerge in oncology as drivers of disease; while our microbiome as well as pathogens exert some of their beneficial and detrimental effects via their own unique metabolism.
Non-invasive imaging is now crossed with high throughput metabolomics and mathematical analysis of metabolic pathways to produce game-changing concepts in physiology and physiopathology.