Jan. 14, 2013

Virus Caught in the Act of Infecting a Cell

The detailed changes in the structure of a virus as it infects an E. coli bacterium have been observed for the first time, report researchers from The University of Texas at Austin and The University of Texas Health Science Center at Houston (UT Health) Medical School in Science Express. moreJan. 14, 2013

Molecular Microscopy: In situ Imaging of Viruses

Investigators at the Virginia Tech Carilion Research Institute have invented a way to directly image biological structures at their most fundamental level and in their natural habitats. The technique is a major advancement toward the ultimate goal of imaging biological processes in action at the atomic level. moreJan. 10, 2013

European Molecular Imaging Meeting EMIM 2013 – Focus on Microscopy

The 8th annual meeting of the European Society for Molecular Imaging (ESMI) will take place from 26-28 May 2013 in Torino, Italy. Molecular imaging is rapidly moving to multimodality approaches, integrating nuclear, radiological and microscopic imaging. To acknowledge this trend, the ESMI strives to integrate the themes of in vivo and molecular microscopy into existing activities of molecular imaging. Novel avenues we recognize include intravital microscopy of disease processes in live animals, fluorescence-guided surgery, and endoscopic detection of diseased tissue.
moreJan. 08, 2013

13th International ELMI Meeting

The European Light Microscopy Initiative (ELMI) is an internationally recognized meeting on Light Microscopy and a unique blend of hands on workshops and lectures on the newest microscopy research and techniques aimed at a life sciences audience. From May 20 to 24, 2013, the 13th conference will be held in Arcachon, near Bordeaux, a very pleasant place south west of France.
moreNov. 02, 2010

X-ray Diffraction Microscopy

H. Jiang and co-workers bridged the visualization gap between 3D optical microscopy and 3D electron microscopy by demonstrating the quantitative 3D imaging of a whole unstained cell by X-ray diffraction microscopy at a resolution of 50-60 nm. Subcellular structures and organelles could be identified and the resolution can be even further improved by cryotechnology. moreOct. 01, 2010

Live-cell Super-resolution Imaging

R. Wombacher and co-workers have generated a chemical tag (trimethoprim, TMP tag) that can be used for direct stochastic optical reconstruction microscopy (dSTORM). A monomeric TMP binding protein that is significantly smaller than fluorescent proteins can be fused to the protein of interest and will bind the cell-permeant TMP-ATTO665 fluorophore conjugate that can subsequently be imaged. The potential of the approach is demonstrated by visualizing human histone H2B in vivo at a resolution of approx. 20 nm. Nature Methods, 7, pp. 717-719 moreApr. 28, 2010

New Views at the Nanoscale

Magnetic resonance imaging has become a standard diagnostic tool for cancer, cardiovascular disease and neurological disorders, among others. MRI is ideally suited to medical imaging because it offers an unparalleled three-dimensional glimpse inside living tissue without damaging the tissue. However, its use in scientific studies has been limited because it can't image anything smaller than several cubic micrometers. Now scientists are combining the 3-D capability of MRI with the precision of a technique called atomic force microscopy. moreMar. 10, 2010

Light Sculpts Three-Dimensional Crystals

Engineering and guiding light by artificial structures is one of the most actual questions in photonics, allowing optical information processing to open new horizons for waveguiding, storing, and processing light. Three-dimensional structures have been a challenge up to now, either due to the complex formation method or the lack of appropriate material. Especially the creation complex quasi crystals that have a number of advantages features as e.g. better control of the transmission features by larger und more homogeneously distributed band gaps, is an actual challenge. more