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High-Resolution Imaging: Visualizing the Malaria Pathogen’s Cellular Skeleton
Apr. 22, 2014

High-Resolution Imaging: Visualizing the Malaria Pathogen’s Cellular Skeleton

The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of the Helmholtz Centre for Infection Research (HZI) in Germany used high-resolution structural biology methods to investigate the different versions of this protein in the parasite in high detail. Their results, published in the scientific journal PLOS Pathogens, may in the future contribute to the development of tailor-made drugs against malaria-a disease that causes more than half a million deaths per year.
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Nanosensors to Visualize Movements and Distribution of Plant Stress Hormone
Apr. 18, 2014

Nanosensors to Visualize Movements and Distribution of Plant Stress Hormone

Biologists at UC San Diego have succeeded in visualizing the movement within plants of a key hormone responsible for growth and resistance to drought. The achievement will allow researchers to conduct further studies to determine how the hormone helps plants respond to drought and other environmental stresses driven by the continuing increase in the atmosphere's carbon dioxide, or CO2, concentration. A paper describing their achievement appears in the scientific journal eLife.
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CPO-9: Charged Particle Optics Conference
Apr. 17, 2014

CPO-9: Charged Particle Optics Conference

Since 1980 the Charged Particle Optics conferences have taken place in sites important for the history of this scientific branch: Giessen, Albuquerque, Toulouse, Tsukuba, Delft, College Park of Maryland, Cambridge and Singapore. The 9th turn was placed in trust of Brno electron microscopists.
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Apr. 17, 2014

New Multiphoton Microscope at the University of Otago

A new $1 million multiphoton microscope will allow University of Otago medical scientists to peer into living brain cells for the first time, and to study the development of neurological diseases such as Alzheimer's.
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Apr. 15, 2014

Tip-Enhanced Raman Imaging of Individual Carbon Nanotubes

Carbon nanotubes are expected to be used in a myriad of applications ranging from military protective clothing to hydrogen storage. Due to their nanometer dimensions, however, the structure and surface chemistry of individual carbon nanotubes cannot be easily studied using conventional techniques. Norihiko Hayazawa and colleagues from the Near Field NanoPhotonics Research Team at the RIKEN Center for Advanced Photonics have now developed a high-resolution microscopy technique that can resolve individual carbon nanotubes under ambient conditions. The work has been published in Nature Communications.
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Sharpening High-Resolution Images Over Large Volumes of Tissue
Apr. 14, 2014

Sharpening High-Resolution Images Over Large Volumes of Tissue

The complexity of biology can befuddle even the most sophisticated light microscopes. Biological samples bend light in unpredictable ways, returning difficult-to-interpret information to the microscope and distorting the resulting image. New imaging technology developed at the Howard Hughes Medical Institute's Janelia Farm Research Campus rapidly corrects for these distortions and sharpens high-resolution images over large volumes of tissue. The research has been published in Nature Methods.
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AFM-based Virtual Nanohand Proposed for Stable Nanomanipulation
Apr. 14, 2014

AFM-based Virtual Nanohand Proposed for Stable Nanomanipulation

Atomic force microscopy (AFM) has become a promising tool for manipulating nano-objects to fabricate nano-structures or nano-devices. However, there are still some challenges facing the development of an AFM based robotic nanomanipulation system, such as the uncertainties associated with AFM tip and nanoparticles, the single point force and interaction between the tip and nanoparticles, and the parameter calibration of models being used. This work was published in IEEE Nanotechnology Magazine.
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Atomic Force Microscopy: Short, Flexible, Reusable AFM Probe
Apr. 11, 2014

Atomic Force Microscopy: Short, Flexible, Reusable AFM Probe

An AFM probe is a cantilever, shaped like a tiny diving board with a small, atomic-scale point on the free end. To measure forces at the molecular scale in a liquid, the probe attaches its tip to a molecule such as a protein and pulls; the resulting deflection of the cantilever is measured. The forces are in the realm of piconewtons, or trillionths of a newton. One newton is roughly the weight of a small apple. The new probe design, described in ACS Nano, is the JILA research group's third recent advance in AFM technology. more
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Imaging & Microscopy Issue 2, 2014 as free epaper or pdf download