High Content Screening is a growing discipline in Life Science Research. Leica Microsystems has therefore launched the HCS A High Content Screening Automation package for confocal research microscopes. Combining the strengths of high-resolution confocal point scanners with the LAS AF Matrix M3 software platform delivers a highly flexible tool for processing large amounts of data and automated imaging in multi dimensions at high speed. The HCS A enables researchers to customize confocal microscopes according to current requirements and challenging life science experiments.
Rare events such as mitosis phases can be detected with the Computer Aided Microscopy (CAM) interface and remote control of the imaging process. Intelligent algorithms designed by researchers analyze images on-the-fly. The system switches from fast pre-scan to high resolution scan mode. Direct imaging of the target cells is accomplished. Basic automation like mosaicing of tissue slides or multi well plate screening in 2D, 3D, and 4D are part of the starting packages. Multiple scan jobs can be assigned either to single chambers or multiple wells. For efficient analysis and storage the acquired data is immediately streamed to local servers. The Open Microscopy Environment (OME) interface simultaneously creates the link to existing image analysis solutions.
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Keywords: Confocal confocal microscopy HCS HCS A High Content Screening Automation image processing Imaging imaging software Leica Microscopy Mircosystems Screening
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