Full Spectral Freedom for Multicolor, Deep In Vivo Imaging: SP8 DIVE Deep In Vivo Explorer

  • Confetti mouse small intestine. Cell lineage tracer. Cyan: CFP, green: GFP, yellow: YFP, red: RFP. Colon cancer research. Sample courtesy of Jacco van Rheenen. University of Utrecht, the Netherlands.Confetti mouse small intestine. Cell lineage tracer. Cyan: CFP, green: GFP, yellow: YFP, red: RFP. Colon cancer research. Sample courtesy of Jacco van Rheenen. University of Utrecht, the Netherlands.

First Spectrally Tunable Solution for Multicolor, Multiphoton Imaging
The new SP8 DIVE Deep In Vivo Explorer is the first fully tunable spectral multiphoton microscope for deep in vivo imaging. The system adapts to every existing and new transgenic marker with only a few mouse clicks. The integrated 4Tune, a unique spectral non-descanned detection unit, replaces conventional, fixed emission filters and provides unlimited flexibility for multicolor deep in vivo imaging.

4Tune – Adapt to New Transgenic Markers
4Tune, the heart of the SP8 DIVE, allows four fluorescent markers to be imaged simultaneously or an infinite number sequentially. It can be equipped with 2, up to 4 detectors, HyD or PMT technology and is fully tunable from 380 up to 800 nm in 1 nm steps. Overlapping emission spectra can easily be separated and sensitivity improved by optimal tuning of the detection bandwidth for any new or existing dye combination.

TuneIR – Adapt to your Scientific Need
All multiphoton excitation lines can be optimally adjusted independently for any objective using the new Vario Beam Expander (VBE). In combination with a beam catcher, the VBE allows for optimized colocalization and the right balance of resolution and depth in line with the research question.

Key Features

  • Spectral Freedom: Fully tunable non-descanned detection with 4Tune. 380 – 800 nm, PMT or Hybrid detection
  • Deep Insight: The Vario Beam Expander allows tuning for deepest insight and finest detail
  • Reproducible scientific results: TuneIR ensures perfect  colocalization and stability for multicolor deep in vivo imaging

 

Contact

Leica Microsystems GmbH
Am Friedensplatz 3
68165 Mannheim
Germany
Phone: +49 621 7028 2801
Telefax: +49 621 7028 8011

Register now!

The latest information directly via newsletter.

To prevent automated spam submissions leave this field empty.