Imaging & Microscopy en Hyperlens Devices: Spiky Nanostructures Capture Life’s Fine Details Optical microscopes that use lenses to bounce photons off objects have trouble distinguishing nanometer-scale objects smaller than the imaging beam’s wavelength, such as proteins and DNA. An innovative ‘hyperlens’ designed at A*STAR can overcome optical diffraction limits by capturing high-resolution information held by short-lived or evanescent waves lurking near a target’s surface. Thu, 23 Feb 2017 10:10:00 +0000 Park Systems Introduces Single Click Software SmartScan Available on Park XE Series Atomic Force Microscopes Park Systems has announced that its AFM operating software SmartScan is now available on Park XE series AFMs.  The software completely automatizes all of the functions of setting up and taking the image once done manually by the operator producing high quality nanoscale imaging in auto mode in five times the normal speed hence drastically boosts productivity single click reliable nanoscale images. Wed, 22 Feb 2017 10:07:00 +0000 Quantum Interpolation: High-Resolution Biomolecule Imaging Determining the exact configuration of proteins and other complex biological molecules is an important step toward understanding their functions, including how they bind with receptors in the body. But such imaging is difficult to do. It usually requires the molecules to be crystallized first so that X-ray diffraction techniques can be applied — and not all such molecules can be crystallized. Fri, 17 Feb 2017 09:59:00 +0000 Oxford Instruments Asylum Research Launches Its New Online European AFM Probe Store Oxford Instruments Asylum Research has launched its new European Atomic Force Microscopy (AFM) Probe Store. Thu, 16 Feb 2017 12:29:00 +0000 Shrinking Atomic Force Microscope to Dime-Sized Device Researchers at The University of Texas at Dallas have created an atomic force microscope on a chip, dramatically shrinking the size — and, hopefully, the price tag — of a high-tech device commonly used to characterize material properties. Thu, 16 Feb 2017 09:10:00 +0000 Measuring Entropy with Scanning Tunneling Microscopy A scanning tunneling microscope (STM), used to study changes in the shape of a single molecule at the atomic scale, impacts the ability of that molecule to make these changes; the entropy of the molecule is changed and, in turn, can be measured. The study led by Empa physicists is published in Nature Communications. Wed, 15 Feb 2017 09:58:00 +0000 Super-Resolution System Reveals Mechanics of Tiny ‘DNA Walker’ Researchers have introduced a new type of “super-resolution” microscopy and used it to discover the precise walking mechanism behind tiny structures made of DNA that could find biomedical and industrial applications. The researchers also demonstrated how the “DNA walker” is able to release an anticancer drug, representing a potential new biomedical technology, said Jong Hyun Choi, an associate professor of mechanical engineering at Purdue University. Tue, 14 Feb 2017 06:38:00 +0000 Andor Launches iXon Life for Fluorescence Microscopy Andor Technology has introduced the ultrasensitive iXon Life Electron Multiplying CCD (EMCCD) camera platform, exclusively for fluorescence microscopy. Featuring single photon sensitive, back-illuminated EMCCD technology and overclocked to market leading frame rate performance, iXon Life is available within a highly accessible price bracket, normally associated with lower cost back-illuminated sCMOS technology. Mon, 13 Feb 2017 14:51:00 +0000 Molecular Switches: New Tools for Super-Resolution Imaging In the journal Scientific Reports, scientists in Bayreuth examine the deliberate switching of individual photochromic molecules. These findings are opening up new research possibilities for visualizing the structures of complex molecules and even entire biological systems. Basic research focusing on photochromic molecules Mon, 13 Feb 2017 12:35:00 +0000 Bruker Announces Acquisition of Hysitron Bruker announced that it has acquired Hysitron, Inc., a technology company in the development, manufacture, and sale of nanomechanical test instrumentation. The acquisition adds Hysitron’s nanomechanical testing instruments to Bruker’s existing portfolio of atomic force microscopes (AFMs), surface profilometers, and tribology and mechanical testing systems. Hysitron’s 2016 revenues were approximately $20 million. Financial details of the transaction were not disclosed. Mon, 13 Feb 2017 08:06:00 +0000 Hamamatsu’s latest CMOS Linear Image Sensor Hamamatsu Photonics introduces the new S13488 CMOS linear image sensor, featuring electronic shutter and gain switching functionalities, as well as high sensitivity in the red, green and blue wavelength ranges of visible light. The S13488 features a sensitivity range of 400-1000nm, as well as a 10MHz maximum video data rate and built-in timing generator, allowing operation with only start and clock pulse. Fri, 10 Feb 2017 10:08:00 +0000 Achromatic Metalens Opens a Broad World of Color Last summer, researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) announced a new, flat lens that could focus light with high efficiency within the visible spectrum. The lens used an ultrathin array of nanopillars to bend and focus light as it passed. The announcement was hailed as a breakthrough in optics and was named among Science Magazine’s top discoveries of 2016. But the lens had a limitation – it could only focus one color at a time. Thu, 09 Feb 2017 08:04:00 +0000 From Zirconia to Yttria By means of ion beam sputtering, unsupported yttria-stabilized zirconia thin films of various compositions are prepared on NaCl single crystal substrates, and are subsequently investigated using transmission electron microscopy and atomic force microscopy. Studies of the unit cell dimensions (by means of selected area electron diffraction) reveal the phase transition from the tetragonal to the cubic polymorph to lie between 8 and 20 mol% Y2O3. Towards a Greener Energy Future Sun, 05 Feb 2017 06:33:00 +0000 High-Resolution Imaging: Revealing New Understanding of Battery Cathode Particles Using advanced imaging techniques, scientists at the Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have been able to observe what exactly happens inside a cathode particle as lithium-ion batteries are charged and discharged. Sat, 04 Feb 2017 03:22:00 +0000 New Range of Multi-Pixel Photon Counters Hamamatsu Photonics have introduced their new range of Multi-Pixel Photon Counters (MPPC), the S13360-VE series. These new COB-package type MPPCs incorporate through-hole electrodes called TSV (through-silicon via). Fri, 03 Feb 2017 15:50:00 +0000 Electron Microscopy: Precise 3D Location and Identification of All 23,000 Atoms in a Nanoparticle Scientists used one of the world’s most powerful electron microscopes to map the precise location and chemical type of 23,000 atoms in an extremely small particle made of iron and platinum (see video). Fri, 03 Feb 2017 07:07:00 +0000 Nanoscopy: Background Suppression for Super-Resolution Light Microscopy Researchers of Karlsruhe Institute of Technology (KIT) have developed a new fluorescence microscopy method: STEDD (Stimulation Emission Double Depletion) nanoscopy produces images of highest resolution with suppressed background. The new method yields an enhanced image quality, which is advantageous when analyzing three-dimensional, densely arranged subcellular structures. STEDD, a further development of the STED method, is now presented in Nature Photonics. Thu, 02 Feb 2017 09:15:00 +0000 Microscopy Plug-And-Play Package Basler now offers an additional Power Pack for microscopy. The complete plug-and-play package contains the Microscopy Pulse 3.3 MP camera with 4:3 sensor format, CMOS sensor by Aptina and which reaches up to 20 frames per second. Wed, 01 Feb 2017 15:46:00 +0000 Taking the Potential of Confocal Microscopy across the Diffraction Barrier Confocal microscopy, which enables scientists to construct 3D representations of objects in the range of hundreds of nanometer, has been the workhorse and method of choice for imaging for decades now and has revolutionized our view of biology and life sciences. Scientists at VIB have taken the potential of confocal microscopy across the diffraction barrier – using innovative software-based image analysis tools. In the past, it was believed that the laws of physics make it impossible for classical confocal microscopy to resolve anything smaller than 200 nanometers. Tue, 31 Jan 2017 09:47:00 +0000 Ultra-Fast Piezo Nanopositioning Stage Nanometer precision and motion control industry company Physik Instrumente (PI) delivers solutions for very small position changes, coupled with speed and high force, in its P-630 nanopositioning stages. Mon, 30 Jan 2017 15:40:00 +0000 First 3D Observation of Nanomachines Working Inside Cells Researchers headed by IRB Barcelona combine genetic engineering, super-resolution microscopy and biocomputation to allow them to see in 3D the protein machinery inside living cells. Published in the journal Cell, the study unveils key functional features of an assembly of proteins that is vital for animals and plants. With this new strategy in hand, it will be possible to study cellular protein machinery in health and in disease. Mon, 30 Jan 2017 11:07:00 +0000 AFM Applied for Interdisciplinary University Research JPK Instruments, a manufacturer of nanoanalytic instrumentation for life sciences and soft matter research, reports the use of their Nano Wizard AFM system at the University of South Australia for smart wound healing, plant toxicology and novel methods of nanoparticle characterization. Fri, 27 Jan 2017 15:30:00 +0000 Electron Holography: The First Glimpse of a Single Protein Proteins are the tools of life. In future, scientists may be able to examine single molecules with an especially gentle method to determine how they are constructed, how they perform their functions in cells, and how they interact with potential drugs. This is possible thanks to holograms of proteins that, for the first time, have produced using very slow electrons by scientists at the University of Zurich and the Max Planck Institute for Solid State Research in Stuttgart, Germany. Thu, 26 Jan 2017 09:17:00 +0000 Toptica Strengthens Customized Solutions & Innovation by Spinning-off Toptica Projects GmbH In order to serve high complexity laser projects more efficiently Toptica Photonics AG has founded its new subsidiary Toptica Projects GmbH. The new entity will be focusing on customized laser solutions, innovation and technology development. In addition, it will become the new home of the company's Guide Star laser activities. The office is also located in Gräfelfing/Munich and operation has started on October 3rd 2016. Thu, 26 Jan 2017 08:39:00 +0000 EBSD Detectors and Visualization Software Bruker has introduced the e-Flash FS and e-Flash HD in a new generation of detectors for electron backscatter diffraction (EBSD) analysis on scanning electron microscopes (SEM). Wed, 25 Jan 2017 09:47:00 +0000