Imaging & Microscopy en Super-Resolution Spectral Imaging to Monitor Dynamic Processes in Real Time Spectroscopy is the study of the interaction between light and matter, offering numerous important applications in fields ranging from materials science to astronomy. A common goal of spectroscopy is improved spectroscopic resolution to provide more detailed information about dynamic processes. Multichannel spectrometers are widely used in spectroscopy because they are compact, strong, and capture high-speed images. However, the resolution of multichannel spectrometers is limited. Fri, 28 Apr 2017 05:12:00 +0000 Fast Surface Reactions at the Nanoscale The catalytic hydrogenation of NO2 on platinum is studied by field emission microscopy, which allows chemical activity to be monitored on samples whose shape and size are close to those of a single nanoparticle. The high lateral resolution of field emission techniques is combined with the high temporal resolution of a high speed camera to reveal the presence of nonlinear kinetics over different spatiotemporal scales. Wed, 26 Apr 2017 05:52:00 +0000 Zeiss Opens New Microscopy Customer Center Zeiss opened the new Zeiss Microscopy Customer Center Europe at the Oberkochen site (Germany). This is the most comprehensive Zeiss Customer Center including light, electron and X-ray microscopy in a single location: here users from Industry and Academia can try out correlative workflows between the different microscopy technologies and also advanced 3D microscopy. Wed, 26 Apr 2017 05:32:00 +0000 Pharmacoscopy: Next-Generation Microscopy A novel microscopy method, developed and patented by scientists from CeMM, allows unprecedented insights into the spatial organization and direct interactions of immune cells within blood and other liquid multi-lineage tissues. The assay, called Pharmacoscopy and published in Nature Chemical Biology, is able to determine the immunomodulatory properties of drugs within large libraries on immune cells in high resolution and high throughput. Wed, 26 Apr 2017 04:52:00 +0000 Chip-Based Nanoscopy: Microscopy in HD Quality Physicists at Bielefeld University and The Arctic University of Norway in Tromsø have developed a photonic chip that makes it possible to carry out super-resolution light microscopy, also called ‘nanoscopy’, with conventional microscopes. In nanoscopy, the position of single fluorescent molecules can be determined with a precision of just a few nanometres, that is, to a millionth of a millimetre. This information can be used to produce images with a resolution of about 20 to 30 nanometres, and thereby ten times that of conventional light microscopy. Tue, 25 Apr 2017 06:25:00 +0000 13th Multinational Congress on Microscopy MCM2017 is jointly organized by 8 societies: Austrian Society for Electron Microscopy (ASEM), Croatian Microscopy Society (CMS), Czechoslovak Microscopy Society (CSMS), Hungarian Society for Microscopy (HSM), Italian Society of Microscopical Sciences (SISM), Serbian Society for Microscopy (SSM), Slovenian Society for Microscopy (SDM) and Turkish Society for Electron Microscopy (TEMD). Mon, 24 Apr 2017 10:42:00 +0000 User Comfort During Long Periods of Routine Microscope Observation Ergonomic and easy to use, the new Olympus CX43 and CX33 microscopes help keep users comfortable during long periods of use, maximizing work efficiency. In high-throughput laboratory environments, user comfort is important for maintaining productivity. The CX43 and CX33 microscopes are designed with features to minimize user fatigue, including: Mon, 24 Apr 2017 08:34:00 +0000 High-Resolution Imaging with Conventional Microscopes MIT researchers have developed a way to make extremely high-resolution images of tissue samples, at a fraction of the cost of other techniques that offer similar resolution. The new technique relies on expanding tissue before imaging it with a conventional light microscope. Two years ago, the MIT team showed that it was possible to expand tissue volumes 100-fold, resulting in an image resolution of about 60 nanometers. Sat, 22 Apr 2017 04:19:00 +0000 Electron Microscopy: Coloring Biomolecules in Tissue An extra detector on an electron microscope can help determine which molecules are found in which parts of a cell. This is what scientists at the UMCG and Delft University of Technology say in an article published in the journal Scientific Reports. ‘This detector enables us to assign a colour to each molecule in a cell’, says Ben Giepmans, the team leader from Groningen. ‘Multicolour electron microscopes are a new addition to medical research, and they could generate interesting results.’ Fri, 21 Apr 2017 06:45:00 +0000 Park Systems Announces Opening of European Headquarters in Heidelberg Park Systems, a manufacturer of atomic force microscopes (AFM) announced the opening of their European Headquarters in Heidelberg, Germany and appointment of Ludger Weisser as General Manager. Wed, 19 Apr 2017 06:02:00 +0000 Cell Imaging: Discover the Allen Cell Explorer The Allen Cell Explorer is the data portal for the Allen Institute for Cell Science, where you can explore the institute's publicly available data, tools and models. The portal provides an unprecedented view into the organizational diversity of human stem cells by combining large-scale 3D imaging data, predictive models, observations of cells, detailed methods, and cell lines available for use in labs around the world.  Explore cell data Thu, 13 Apr 2017 03:15:00 +0000 Quantum Dots Open New Window for Biological Imaging For certain frequencies of short-wave infrared light, most biological tissues are nearly as transparent as glass. Now, researchers have made tiny particles that can be injected into the body, where they emit those penetrating frequencies. The advance may provide a new way of making detailed images of internal body structures such as fine networks of blood vessels. Wed, 12 Apr 2017 03:28:00 +0000 Label-Free Microscopy: Novel Lens for Super-Resolution Imaging The optical microscope is a critical equipment for scientific research and failure inspection in high precision industries. However, for centuries, the imaging resolution of microscopes is fundamentally limited by the diffraction limit of light. Existing efforts to break this fundamental diffraction limit through various technologies suffer from limitations such as a near-field operation, which requires the sample to be close to the microscope, or the dyeing of samples, which is an invasive process that affects the quality of the sample. Tue, 11 Apr 2017 07:07:00 +0000 Meet Us at Focus On Microscopy in Bordeaux this Week Focus On Microscopy is just running in Bordeaux. The FOM2017 conference takes place at the Palais des Congrès de Bordeaux, Convention Center, Avenue Jean Gabriel, Domergue. You can find Wiley with our magazine Imaging & Microscopy at booth #8. Come by and meet Dr. Stefanie Krauth. We look forward to seeing you! Mon, 10 Apr 2017 12:30:00 +0000 X-Ray Study Reveals Long-Sought Insights Into Potential Drug Target X-ray studies done in part at the Department of Energy’s SLAC National Accelerator Laboratory have produced surprising insights into the workings of a hormone receptor associated with blood pressure regulation. Researchers believe it could be a target for new medicines related to cardiovascular conditions, neuropathic pain and tissue growth. Mon, 10 Apr 2017 08:21:00 +0000 Hitachi map 3D Software: Dedicated Software for Scanning Electron Microscopy A dedicated software for Scanning Electron Microscopy based on Mountains Technology has been introduced by Hitachi High-Technologies. Thanks to the partnership between Hitachi High-Technologies and Digital Surf, users now have full access to a set of powerful tools for visualizing, analyzing and reporting on their data. This includes: Wed, 05 Apr 2017 07:45:00 +0000 New Electron Microscope Sees More than an Image The electron microscope, a powerful tool for science, just became even more powerful, with an improvement developed by Cornell physicists. Their electron microscope pixel array detector (EMPAD) yields not just an image, but a wealth of information about the electrons that create the image and, from that, more about the structure of the sample. Fri, 31 Mar 2017 10:22:00 +0000 Keep your Feet on the Ground! For most sample preparation methods of rare and difficult objects, especially single cells or low cell numbers of precious material, the long lasting preparation and embedding procedure turns out to be a lottery. On the other hand recovery of single cells becomes more and more requested. With a simple, old but not old-fashioned preparation trick we are able to recover 100% of cells meant for analysis by transmission or scanning electron microscopy [1]. Introduction Wed, 29 Mar 2017 04:54:00 +0000 “Cysteine Rose” Wins Electron Microscopy Image Contest Italian Institute of Technology’s Andrea Jacassi is the grand prize winner of the Sixth Annual 2016 Thermo Fisher Scientific Electron Microscopy image contest for his “Cysteine Rose” image. The image, acquired using the FEI Helios NanoLab 650 DualBeam, focused ion beam/scanning electron microscope (FIB/SEM) and was selected by a vote of Thermo Fisher employees from more than 270 entries. Jacassi will receive a Canon EOS 80D DSLR camera package. Tue, 28 Mar 2017 06:22:00 +0000 Single-Angle Ptychography Allows 3D Imaging of Stressed Materials Everyone reacts differently under stress — even the relatively orderly atoms in a crystal. If scientists could get a clear picture of how planes of atoms shift and squeeze under stress, they could make use of those properties to provide emerging technologies, like nanoelectronics and next-generation semiconductor components, with extra speed or functionalities. However, creating this picture requires new techniques for imaging atoms in materials and their behavior in different environments. Mon, 27 Mar 2017 12:16:00 +0000 Combine High Performance and Ease of Use with the Fluoview FV3000 Olympus’ Fluoview FV3000 represents the best of both worlds in high-resolution live cell imaging and user friendly, ergonomic design. In recognition of this combination, the jury of the 2017 iF design awards have recently awarded an iF product award to the FV3000 for exceptional product design. Mon, 27 Mar 2017 08:37:00 +0000 Multi-Parameter Microscopy Aids Design of Improved Optoelectronic Devices The National Physical Laboratory (NPL) has developed a novel measurement method, providing simultaneous topographical, electrical, chemical and optical microscopy (STEOM) at the nanoscale for the first time. The new method can be used to optimize the performance of optoelectronic devices such as organic solar cells, sensors and transistors. Mon, 27 Mar 2017 06:29:00 +0000 New Opportunities for Live Cell Nanoscopy The STED WHITE objective Leica HC PL APO 93x/1.3 Glyc motCORR is a optic designed for Stimulated Emission Depletion (STED) imaging and resolves at the nanoscale. Mon, 27 Mar 2017 05:57:00 +0000 Cell-Permeant Fluorescent Nanocomposites Different types of molecular and nanoscale fluorophores are being developed for fluorescent imaging of live cells. Here we present their novel types and novel compositions. The dyes incorporated into nanostructures and their metal coordination complexes as well as carbon nanodots penetrate easily into the cell with the lack of toxicity, forming stable images. They are prospective for further functionalization for targeting and contrasting cell organelles and for biosensing. Introduction Mon, 27 Mar 2017 04:18:00 +0000 Transmission Electron Microscopy: Chemical Reactions 'Filmed' at the Single-Molecule Level Scientists have succeeded in ‘filming’ inter-molecular chemical reactions – using the electron beam of a transmission electron microscope (TEM) as a stop-frame imaging tool (see video). They have also discovered that the electron beam can be simultaneously tuned to stimulate specific chemical reactions by using it as a source of energy as well as an imaging tool. Thu, 23 Mar 2017 08:38:00 +0000