Imaging & Microscopy http://www.imaging-git.com/rss.xml en A New Type of Laser http://www.imaging-git.com/news/new-type-laser University of Würzburg physicists have succeeded in creating a new type of laser. Its operation principle is completely different from conventional devices, which opens up the possibility of a significantly reduced energy input requirement. The researchers report their work in Nature. http://www.imaging-git.com/news/new-type-laser Fri, 24 May 2013 03:57:00 +0000 Heinrich Rohrer, the Co-inventor of the Scanning Tunneling Microscope, Passed Away http://www.imaging-git.com/news/heinrich-rohrer-co-inventor-scanning-tunneling-microscope-passed-away The co-inventor of the scanning tunneling microscope, Dr. Heinrich Rohrer, passed away on the evening of May 16, 2013. He was 79. Heinrich Rohrer, IBM Fellow and Nobel Laureate, joined the IBM Research Laboratory in Zurich, Switzerland, in December of 1963, where he worked for 34 years. After hiring a young scientist named Gerd Binnig in the late 1970s, the two started collaborating, brought closely together by their backgrounds in superconductivity and their fascination with atomic surfaces. The two scientists grew increasingly frustrated by the limits of the tools then available to study the distinct characteristics of atomic surfaces, so they decided to build their own, something that would be capable of seeing and manipulating atoms at the nanoscale level. http://www.imaging-git.com/news/heinrich-rohrer-co-inventor-scanning-tunneling-microscope-passed-away Thu, 23 May 2013 09:17:00 +0000 Improved Imaging Technique Solve Key Puzzle of LED Efficiency http://www.imaging-git.com/news/improved-imaging-technique-solve-key-puzzle-led-efficiency From the high-resolution glow of flat screen televisions to light bulbs that last for years, light-emitting diodes (LEDs) continue to transform technology. The celebrated efficiency and versatility of LEDs-and other solid-state technologies including laser diodes and solar photovoltaics-make them increasingly popular. Their full potential, however, remains untapped, in part because the semiconductor alloys that make these devices work continue to puzzle scientists. http://www.imaging-git.com/news/improved-imaging-technique-solve-key-puzzle-led-efficiency Thu, 23 May 2013 06:25:00 +0000 Visualize the Quantum Behavior of Large Molecules in Real Time http://www.imaging-git.com/products/image-processing/visualize-quantum-behavior-large-molecules-real-time The group of Professor Markus Arndt at the University of Vienna, Austria, has shown the diffraction of single, massive molecules at a grating in an unambiguous demonstration of the wave-particle duality of quantum physics. http://www.imaging-git.com/products/image-processing/visualize-quantum-behavior-large-molecules-real-time Fri, 17 May 2013 08:56:00 +0000 Cobolt Calypso 491 nm: A High Performance DPSS Laser for Demanding Analytical Applications http://www.imaging-git.com/products/light-microscopy/cobolt-calypso-491-nm-high-performance-dpss-laser-demanding-analytical-app The Swedish DPSS lasers manufacturer Cobolt has recently released a higher power version of its Cobolt Calypso 491nm.The laser is now available on the 05-01 Series single frequency platform with an output power of 200 mW CW. Lower power versions (25 mW-150 mW) can be found on the 04-01 Series SLM platform.  http://www.imaging-git.com/products/light-microscopy/cobolt-calypso-491-nm-high-performance-dpss-laser-demanding-analytical-app Fri, 17 May 2013 05:12:00 +0000 Improving Drug Delivery with Macrophage Targeting http://www.imaging-git.com/applications/improving-drug-delivery-macrophage-targeting The majority of diseases are treatable, but ensuring that the drug compound reaches its target site remains a constant challenge. This study describes an advanced stealth liposome approach of drug delivery, employing confocal laser scanning fluorescence microscopy to evaluate the selective targeting of macrophages. http://www.imaging-git.com/applications/improving-drug-delivery-macrophage-targeting Thu, 16 May 2013 11:06:00 +0000 Scanning Electrochemical Microscopy: Measuring Oxygen Consumption of Individual Cells http://www.imaging-git.com/news/scanning-electrochemical-microscopy-measuring-oxygen-consumption-individual-cells How active a living cell is can be seen by its oxygen consumption. The method for determining this consumption has now been significantly improved by chemists in Bochum. The problem up to now was that the measuring electrode altered the oxygen consumption in the cell's environment much more than the cell itself. "We already found that out twelve years ago," says Prof. Dr. Wolfgang Schuhmann from the Department of Analytical Chemistry at the Ruhr-Universität (Germany). "Now we have finally managed to make the measuring electrode an spectator." Together with his team, he reports in the "International Edition" of the journal Angewandte Chemie. http://www.imaging-git.com/news/scanning-electrochemical-microscopy-measuring-oxygen-consumption-individual-cells Tue, 14 May 2013 05:46:00 +0000 Unmask the Hidden without Probes: CARS http://www.imaging-git.com/applications/unmask-hidden-without-probes-cars Fluorescence microscopy assumed a pivotal role in cell biology once it was possible to stain cell components selectively by fluorescing dyes. One of the first explorers of targeted stainings, Paul Ehrlich, had the idea that something that stains specifically should also kill specifically - which was associated with the term "magic bullet", the essential idea of chemotherapy. His group discovered Salvarsan, a tailored drug against syphilis - though not specific enough not to cause substantial side effects. http://www.imaging-git.com/applications/unmask-hidden-without-probes-cars Mon, 13 May 2013 11:00:00 +0000 X-ray Free-electron Lasers: Observing the Movement of Electrons around Atoms http://www.imaging-git.com/news/x-ray-free-electron-lasers-observing-movement-electrons-around-atoms X-ray free-electron lasers (XFELs) produce higher-power laser pulses over a broader range of energies compared with most other x-ray sources. Although the pulse durations currently available are enormously useful for the study of materials, even shorter pulses are needed to observe features such as electrons at subatomic scales. Takashi Tanaka from the Riken SPring-8 Center has now proposed a theoretical pulse-amplification scheme that allows for the production of ultrashort x-ray pulses at extremely high energies. http://www.imaging-git.com/news/x-ray-free-electron-lasers-observing-movement-electrons-around-atoms Mon, 13 May 2013 07:01:00 +0000 Photonic Science Introduces sCMOS Cameras with Open Source Software http://www.imaging-git.com/products/image-processing/photonic-science-introduces-scmos-cameras-open-source-software Photonic Science has introduced a new range of sCMOS camera for microscopy and spectroscopy applications. http://www.imaging-git.com/products/image-processing/photonic-science-introduces-scmos-cameras-open-source-software Tue, 07 May 2013 06:14:00 +0000 2013 FEI Image Contest http://www.imaging-git.com/news/2013-fei-image-contest FEI invites owners and users to submit their best images from an FEI instrument. We are continuing our partnership with National Geographic on the upcoming film "Mysteries of the Unseen World". All images submitted will be considered for inclusion in the film's promotional materials. http://www.imaging-git.com/news/2013-fei-image-contest Mon, 06 May 2013 09:27:00 +0000 Quantum-assisted Nano-imaging of Living Organism http://www.imaging-git.com/news/quantum-assisted-nano-imaging-living-organism In science, many of the most interesting events occur at a scale far smaller than the unaided human eye can see. Medical researchers might realize a range of breakthroughs if they could look deep inside living biological cells, but existing methods for imaging either lack the desired sensitivity and resolution or require conditions that lead to cell death, such as cryogenic temperatures. Recently, however, a team of Harvard University-led researchers working on DARPA's Quantum-Assisted Sensing and Readout (QuASAR) program demonstrated imaging of magnetic structures inside of living cells. Using equipment operated at room temperature and pressure, the team was able to display detail down to 400 nanometers, which is roughly the size of two measles viruses. http://www.imaging-git.com/news/quantum-assisted-nano-imaging-living-organism Mon, 06 May 2013 08:07:00 +0000 Analytik Jena Establishes Subsidiary in Thailand http://www.imaging-git.com/news/analytik-jena-establishes-subsidiary-thailand Analytik Jena, a manufacturer of analytical instrumentation technology, life science instruments and optoelectronics, has established a new subsidiary, Analytik Jena Far East (Thailand) Ltd., giving it a presence in the Southeast Asian market. Analytik Jena is using this new company to bolster its activities in the Southeast Asian market, increase its regional service for the sales partners and customers operating there and expand its regional sales activities. In future, the company wants to strengthen its core business of Analytical Instrumentation from Bangkok with its ninth foreign subsidiary. http://www.imaging-git.com/news/analytik-jena-establishes-subsidiary-thailand Mon, 06 May 2013 07:26:00 +0000 Ted Pella Introduces Pelco Graphene TEM Support Films http://www.imaging-git.com/products/electron-and-ion-microscopy/ted-pella-introduces-pelco-graphene-tem-support-films Ted Pella, Inc has announced the availability of the new research-ready Pelco graphene TEM support films. The films are supported by lacey carbon film on a 300 mesh copper grid. The single, continuous graphene sheet covers the entire 300 mesh area of the TEM grid. This creates a usable area of around 75% of the TEM grid, leaving plenty of space for specimens or experiments. The Pelco graphene TEM support films with the large area continuous film can be used directly out of the box. http://www.imaging-git.com/products/electron-and-ion-microscopy/ted-pella-introduces-pelco-graphene-tem-support-films Mon, 06 May 2013 05:16:00 +0000 Bug’s View Inspires New Digital Camera’s Unique Imaging Capabilities http://www.imaging-git.com/news/bug-s-view-inspires-new-digital-camera-s-unique-imaging-capabilities An interdisciplinary team of researchers has created the first digital cameras with designs that mimic those of ocular systems found in dragonflies, bees, praying mantises and other insects. This class of technology offers exceptionally wide-angle fields of view, with low aberrations, high acuity to motion, and nearly infinite depth of field. http://www.imaging-git.com/news/bug-s-view-inspires-new-digital-camera-s-unique-imaging-capabilities Thu, 02 May 2013 09:03:00 +0000 New Super-resolution Microscopy Technique without Fluorescent Dyes http://www.imaging-git.com/news/new-super-resolution-microscopy-technique-without-fluorescent-dyes Researchers have found a way to see synthetic nanostructures and molecules using a new type of super-resolution optical microscopy that does not require fluorescent dyes, representing a practical tool for biomedical and nanotechnology research."Super-resolution optical microscopy has opened a new window into the nanoscopic world," said Ji-Xin Cheng, an associate professor of biomedical engineering and chemistry at Purdue University. http://www.imaging-git.com/news/new-super-resolution-microscopy-technique-without-fluorescent-dyes Thu, 02 May 2013 07:08:00 +0000 New Metrics for X-ray and Neutron Analysis of Flexible Macromolecules http://www.imaging-git.com/news/new-metrics-x-ray-and-neutron-analysis-flexible-macromolecules A dramatic leap forward in the ability of scientists to study the structural states of macromolecules such as proteins and nanoparticles in solution has been achieved by a pair of researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab). The researchers have developed a new set of metrics for analyzing data acquired via small angle scattering (SAS) experiments with X-rays (SAXS) or neutrons (SANS). Among other advantages, this will reduce the time required to collect data by up to 20 times. http://www.imaging-git.com/news/new-metrics-x-ray-and-neutron-analysis-flexible-macromolecules Tue, 30 Apr 2013 08:01:00 +0000 Transmission Electron Microscopy: Imaging Nanoparticles in Action http://www.imaging-git.com/news/transmission-electron-microscopy-imaging-nanoparticles-action The macroscopic effects of certain nanoparticles on human health have long been clear to the naked eye. What scientists have lacked is the ability to see the detailed movements of individual particles that give rise to those effects. In a recently published study, scientists at the Virginia Tech Carilion Research Institute invented a technique for imaging nanoparticle dynamics with atomic resolution as these dynamics occur in a liquid environment. The results will allow, for the first time, the imaging of nanoscale processes, such as the engulfment of nanoparticles into cells. http://www.imaging-git.com/news/transmission-electron-microscopy-imaging-nanoparticles-action Mon, 29 Apr 2013 09:07:00 +0000 New Imaging Technology Could Reveal Cellular Secrets http://www.imaging-git.com/news/new-imaging-technology-could-reveal-cellular-secrets Researchers have married two biological imaging technologies, creating a new way to learn how good cells go bad. "Let's say you have a large population of cells," said Corey Neu, an assistant professor in Purdue University's Weldon School of Biomedical Engineering. "Just one of them might metastasize or proliferate, forming a cancerous tumor. We need to understand what it is that gives rise to that one bad cell." http://www.imaging-git.com/news/new-imaging-technology-could-reveal-cellular-secrets Mon, 29 Apr 2013 07:30:00 +0000 Ultra-high Resolution Microscopy: Cellular Networks Up Close http://www.imaging-git.com/news/ultra-high-resolution-microscopy-cellular-networks-close High-powered microscopic techniques give scientists a detailed view of a critical component of the cellular infrastructure. The cellular interior is criss-crossed by protein-based cables known as microtubules, each formed from 13 ‘protofilaments' composed of the protein tubulin. Microtubules are also associated with a host of other specialized proteins that help coordinate the transport of molecular cargoes and link microtubules to intracellular structures. http://www.imaging-git.com/news/ultra-high-resolution-microscopy-cellular-networks-close Fri, 26 Apr 2013 08:10:00 +0000 Multilayer Laue Lenses Enable Studies of Nanostructures with Ultra-high Resolution http://www.imaging-git.com/news/multilayer-laue-lenses-enable-studies-nanostructures-ultra-high-resolution Microscopes have been a centerpiece of experimental science since at least the 16th century, providing a window into the material world at extraordinarily small scales. As the structures examined decrease in size - some measuring just billionths of a meter - capturing an x-ray image at high spatial resolution while retaining sufficient imaging contrast becomes more difficult. http://www.imaging-git.com/news/multilayer-laue-lenses-enable-studies-nanostructures-ultra-high-resolution Thu, 25 Apr 2013 08:59:00 +0000 Digital Surf Announces the Official Release of Mountains 7 Software http://www.imaging-git.com/products/electron-and-ion-microscopy/digital-surf-announces-official-release-mountains-7-software Digital Surf has announced the official release of its Mountains 7 software for surface imaging and metrology.  http://www.imaging-git.com/products/electron-and-ion-microscopy/digital-surf-announces-official-release-mountains-7-software Wed, 24 Apr 2013 05:00:00 +0000 Ultra-fast High-resolution Imaging in Real Time http://www.imaging-git.com/news/ultra-fast-high-resolution-imaging-real-time Ultra-fast high-resolution imaging in real time could be a reality with a new research discovery led by the University of Melbourne. The scientists have demonstrated that ultra short durations of electron bunches generated from laser-cooled atoms can be both very cold and ultra-fast. The results were published in Nature Communications. http://www.imaging-git.com/news/ultra-fast-high-resolution-imaging-real-time Tue, 23 Apr 2013 10:49:00 +0000 High Throughput Nanopositioning http://www.imaging-git.com/products/light-microscopy/high-throughput-nanopositioning Queensgate Instruments has introduced OSM-Z-100B. The objective scanning mechanism uses Dual Sensor Technology to achieve high dynamics and precision in microscope objective focusing. http://www.imaging-git.com/products/light-microscopy/high-throughput-nanopositioning Tue, 23 Apr 2013 08:25:00 +0000 University College London Uses Evactron Plasma Technology http://www.imaging-git.com/products/electron-and-ion-microscopy/university-college-london-uses-evactron-plasma-technology XEI Scientific Inc. has reported that the University College London (UCL) is using an Evactron plasma technology for cleaning their scanning electron microscopy chamber. http://www.imaging-git.com/products/electron-and-ion-microscopy/university-college-london-uses-evactron-plasma-technology Mon, 22 Apr 2013 12:48:00 +0000