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Quantitative Microscopy without Lenses
Dec. 27, 2010

Quantitative Microscopy without Lenses

Minimisation of the geometric restrictions and image infidelities imposed by imperfect physical focussing devices has been the subject of microscopy research for many decades, as has the development of ways to recover information-rich phase data lost by detectors that are sensitive only to illumination intensity. more
Towards Automated AFM-based Nanohandling of DNA, SAMs and CNTs
Dec. 21, 2010

Towards Automated AFM-based Nanohandling of DNA, SAMs and CNTs

Besides its ability of high resolution imaging, the Atomic Force Microscope (AFM) has been recognized as a valuable instrument for manipulation at the nanoscale. The characterization and manipulation of Carbon Nanotubes (CNTs) and DNA or the prototypical surface structuring of sensitive elements for biosensors are main applications for AFM-based nanohandling. The relatively low throughput induced by the sequential character of the AFM is one of the major drawbacks that arise, if the AFM is used as a robot for nanomanipulation. more
Index Tailored Optical Fibers for Plasmon Enhanced Scanning Near-field Optical Microscopy and Spectroscopy
Dec. 20, 2010

Index Tailored Optical Fibers for Plasmon Enhanced Scanning Near-field Optical Microscopy and ...

Scanning near-field optical microscopy (SNOM) and spectroscopy allow sub-wavelength spatial resolution for gathering a diversity of information typical for optical spectroscopy, e.g. Raman, infrared absorption, and dielectric dispersion. Applications range from fundamental and bio-medical science over material characterization to investigations of fully-functional devices, all on the nanometer length scale. more
Vibrational Spectroscopy
Dec. 20, 2010

Vibrational Spectroscopy

Optical spectroscopy offers multiple advantages over other identification techniques because it is highly sensitive to the biochemical nature of materials, can offer great spatial resolution when needed and can be made highly portable. This has made it the technique of choice for multiple applications ranging from remote sensing to disease diagnosis. For instance, needs in remote sensing in the atmosphere or in the battlefield have driven significant developments in devices and techniques using infrared and Raman spectroscopy [1, 2, 3]. more
Expanding Compositional Imaging with AFM
Dec. 20, 2010

Expanding Compositional Imaging with AFM

In atomic force microscopy (AFM) [1] a miniature cantilever with a sharp tip at the end is applied for high-resolution profiling of samples and probing of their local properties. The probe is scanning the sample either in contact or oscillatory mode with the later most applicable to soft materials. High precision scanning and the sensitive detection of tip-sample force enable AFM visualization of surface structures as small as atomic lattices and single molecules. An advantage of the technique is applicability in various environments including liquids and vapors. more
Characterization of Polyethylene Oxide (PEO) Nanofibers by Atomic Force Microscope (AFM)
Dec. 16, 2010

Characterization of Polyethylene Oxide (PEO) Nanofibers by Atomic Force Microscope (AFM)

We investigate the properties of the Polymers nanofibers for its application in the sensors area. Hence, are very important the geometrical, mechanical and electrical properties of the fibers. We produce the fibers by electrospinning; this method is a simple and quick technique for producing fibers with nanoscale diameters from a wide range of materials. In this process, a strong electric field causes a viscous solution to form a Taylor cone, from which a thin fluid jet is formed. This fluid jet may harden by a variety of processes and become a continuous fiber. more
Microscopic Imaging of Rosette Nanotubes
Dec. 13, 2010

Microscopic Imaging of Rosette Nanotubes

The characterization of self-assembled rosette nanotubes (RNTs), which are soft organic nanomaterials, can be challenging because of their small dimensions (diameter 3-8 nm) and their sensitivity to damage by microscopy techniques. Consequently, proper sample preparation and optimized microscopy conditions are necessary for successful characterization. In this paper, the critical factors that strongly affect the quality of the structural information obtained for RNTs are presented (fig. 1) more
To Bead or Not To Bead?
Nov. 26, 2010

To Bead or Not To Bead?

In a large core microscopy facility, instrument performance can decline over time, introducing optical artifacts or distortions into the data. We have selected two commercially available tools which can be used in any facility to monitor changes in optical performance. Using these tools, we have identified objective and alignment problems not visible through typical image collection. A similar approach could be of great benefit to other core microscopy facilities in quality assurance. more
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