Jul. 19, 2010
We report on the development and testing of an integrated web-based project- and access-management system (PAMS) to improve the management of shared resources by technical platforms in a scientific research environment. moreJul. 05, 2010
Fluorescence microscopy combines the power of high performance optical components and digital image analysis. The emission signals of fluorescent dyes show a significant spectral crosstalk which inevitably increases with the number of fluorescent dyes used. However, it is possible to significantly reduce the effects of spectral crosstalk by the application of spectral imaging and spectral unmixing techniques. Spectral imaging is the combination of computer vision and spectroscopy.
Epidemiology of Breast Cancer moreJun. 25, 2010
This article briefly describes the basics of both optical and atomic force microscopy, followed by a discussion of some of the technical challenges of integrating these two distinct imaging modalities. In certain cases, the benefits and disadvantages of different approaches to design and integration are discussed. Lastly, a few examples of successful application of these combined imaging modalities are presented. moreJun. 23, 2010
80kV- High Resolution Transmission Electron Microscopy (HRTEM) characterization of micromechanically cleaved graphene shows in real- time atomically resolved dynamics of the carbon atoms in graphene constrictions. During electron irradiation, processes of hole formation generate graphene constrictions and eventually lead to stable single carbon atom chains. Carbon chains also occur between carbonaceous adsorbates and looping along graphene edges. moreMay. 03, 2010
Optical microscopes are subject to the diffraction barrier of light which imposes an optical resolution limit of approximately 200 nm in the imaging plane. dSTORM enables super-resolution imaging with commercially available standard fluorophores and probes at a resolution of ~ 20 nm even in living cells. moreApr. 19, 2010
Hydrothermal decomposition of KMnO4 in the acidic environment in the presence of Fe3+(aq) ions leads to the formation of α-MnO2 nanotubes. The morphology evolution from the sponge-like spheres to the nanotubes as a function of reaction time was imaged by FE-SEM and TEM. The presence of iron in nanotubes was unambiguously confirmed by STEM-EELS measurement across the nanotube diameter.
Introduction moreMar. 31, 2010
Organic and mineral samples, containing light elements like oxygen, nitrogen or beryllium have been analyzed using an attachable X-ray optic with an SDD in SEM. Compared to the measurements without the additional optic, there is a significant increase of the detection sensitivity for X-rays in the energy range below 1 keV. In contrast the spectrum above 1 keV is not affected. The optic can provide similar intensities for low and high energy X-ray lines even at high accelerating voltage.
Introduction moreMar. 24, 2010
We have shown that 50 nm details can be distinguished in x-ray images using a compact laboratory set-up. A novel emitter design inside the x-ray source produces a very small, stable focal spot and prevents diffraction limiting effects. Due to unlimited depth of focus, the source doesn't impose a limit on the specimen size that can be reconstructed by 3D x-ray nano-tomography.