Nov. 04, 2009
Fluorapatite-gelatine nanocomposites serve as model system for mineralization steps of teeth and bone. The biomimetic composites show a hierarchical structural shape development starting from a hexagonal prismatic seed via dumbbell states and ending up with slightly notched spheres. This complex morphogenesis is caused by protein fibrils which are integrated into the nanocomposite superstructure. As evidenced by electron holography an intrinsic electric dipole field is generated by parallel alignment of nanocomposite subunits. moreNov. 04, 2009
The ITRS requires the integration of dielectric materials with effective dielectric constant (k) lower than 2.8. This is achieved using porous SiOCH. Unfortunately during integration in the devices, damages are introduced in the low-k layer by CMP. The impact of these damages on the microstructure and the electronic properties are studied using HAADF imaging and Valence Electron Energy Loss Spectroscopy in TEM environment. Results are compared to low-k capped with an etch stop layer. moreNov. 04, 2009
Fuel cells are expected to play a major role in the future energy supply, especially polymer electrolyte membrane fuel cells could become an integral part in future cars. Reduction of degradation of fuel cell performance while keeping fuel cell cost under control is the key for an introduction into mass markets. moreNov. 04, 2009
Proteins that copy and edit DNA help protect cells from attack by removing viral DNA insertions. They are thought to reach their target sequence by "sliding", "hopping" and "jumping" along DNA strands. Observing this behavior has proved hard, however, due to its speed of action. We discuss a recent research project that used a high-speed camera to observe - for the first time - the sliding and jumping of EcoRV, a restriction enzyme, along DNA molecules. moreNov. 04, 2009
We want the electronic gadgets of tomorrow to be smaller and lighter, but also faster and more powerful: Whether MP3 players, camera mobile phones, navigation systems or notebooks, all have to be compact but also able to store increasingly large amounts of music, images, films or maps, and process them quickly. moreNov. 04, 2009
Normal and diseased tissues are complex mixtures of different cell populations. A better understanding of protein expression changes that occur during
diseases needs sensitive and specific technologies for each of these cell types. Mass spectrometry based tissue imaging (MALDI-MSI) is a newly developed technique, allowing the visualization of proteins, peptides, lipids and small molecules directly on thin sections cut from fresh frozen or fixed paraffin embedded tissues. moreNov. 04, 2009
The high resolution and sensitivity of electron microscopy is a valuable ancillary tool or gold standard in pathological diagnosis. The conventional sample turnaround time for processing in the lab can be significantly reduced from days to hours by the microwave technology. Microwave-assisted tissue processing, in combination with digital image acquisition, enables a "same-day" diagnosis in urgent clinical cases. Ultrastructural telepathology allows instant and live second opinion retrieval from a remote expert worldwide.
Introduction moreNov. 04, 2009
We use the intense light coming from a third generation synchrotron source to perform computed tomography (CT) with micro-resolution and high material contrast. This unique tool allows for shedding light on methodical errors which are involved when applying classical histomorphometry. The tomographic approach using X-rays is not only non-destructive, it also allows for an analysis in a true 3D manner. Thus, it delivers knowledge of which is important to fully understand e. g. bone regeneration.