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Fundamental Knowledge - Part 4
Sep. 01, 2008

Fundamental Knowledge - Part 4

Fundamental Knowledge - Part 4: Digitial Imaging Cameras: Deciphering Specifications. In the first instalments of this article series we looked at the theory behind microscopy: how a small facet of a sample can be magnified and focused efficiently and effectively at the focal plan of the user's eyes or the imaging device. In this article, we look at the surprisingly complex world of digital microscopy cameras and how to find the best one for each research task.
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Optical Simulation Improves Biomedical Devices: Virtual Prototyping Software
Sep. 01, 2008

Optical Simulation Improves Biomedical Devices: Virtual Prototyping Software

Optical Simulation Improves Biomedical Devices: Virtual Prototyping Software. Photonic devices play an indispensable role in today's bio-medical industry. For the last quarter century, timely design and delivery to market of these new technologies has been possible only with the aid of sophisticated software tools and experienced optical engineers. Modern optical engineering tools such as FRED help accelerate the pace of innovation in the biomedical community by enabling its members to participate more fully in the process. more
Intracytoplasmic Morphologically Selected Sperm Injection
Sep. 01, 2008

Intracytoplasmic Morphologically Selected Sperm Injection

Intracytoplasmic Morphologically Selected Sperm Injection: The success of in vitro fertilisation techniques such as intracytoplasmic sperm injection (ICSI) depends critically on selection of the most healthy sperm for injection into the oocyte. Intracytoplasmic morphologically selected sperm injection (IMSI) is a high magnification light microscopy imaging method that is being used increasingly to select sperm for ICSI. IMSI has been shown to increase pregnancy rates and reduce abortion rates compared to routine ICSI-IVF. more
Aberration Corrected STEM and EELS: Atomic Scale Chemical Mapping
Sep. 01, 2008

Aberration Corrected STEM and EELS: Atomic Scale Chemical Mapping

Aberration Corrected STEM and EELS: Atomic Scale Chemical Mapping - The ultimate aim of an analytical technique applied to a solid material could be stated as the identification and mapping of the constituent atoms and their bonding in three dimensions. Hitherto, this was almost always achieved by diffraction methods averaging over many identical structures and, where it can be used, this remains the most powerful approach. more
Correlative 3D Microscopy: CLSM & FIB/SEM Tomography
Sep. 01, 2008

Correlative 3D Microscopy: CLSM & FIB/SEM Tomography

Correlative 3D Microscopy: CLSM & FIB/SEM Tomography -  A Study of Cellular Entry of Vaccinia Virus. Subcellular structural investigation on single cells or tissue samples requires the coupling of optimal structural preservation with detailed imaging at the light and electron microscopic level. more
TEM Nanolaboratory: Physical Measurements
Sep. 01, 2008

TEM Nanolaboratory: Physical Measurements

TEM Nanolaboratory: Physical Measurements - With the rapidly growing development in nanosciences, the requirement for realising physical measurements on well-identified and -characterised individual nanostructures has become unavoidable to complement the vision brought by average measurements on an ensemble of insufficiently characterised nanostructures. more
Electron Beam Induced Damage: TEAM0.5 Atom-by-atom Investigation
Sep. 01, 2008

Electron Beam Induced Damage: TEAM0.5 Atom-by-atom Investigation

Electron Beam Induced Damage: TEAM0.5 Atom-by-atom Investigation - A next generation electron microscopes is currently being developed by the Department of Energy as a collaborative effort to redesign the instruments around aberration corrected optics [1]. Within this project, the TEAM 0.5 prototype microscope is currently being commissioned. The instrument is equipped with a high brightness gun and a monochromator [2]. more
Time-resolved Acoustic Microscopy
Aug. 01, 2008

Time-resolved Acoustic Microscopy

Recent growth of interest in the mechanical properties of cells demands for the development of new techniques for the assessement of these atributes. Acoustic microscopy equipped with time-resolved signal ­analysis provides unique possibilities for the determination of dynamical processes in biological cells and allows probing biological specimen with submicrometre resolution. more
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