Jul. 01, 2007
International Meeting on AFM in Biology and Medicine (AFM BioMed): Atomic force microscopy (AFM) is gaining recognition as a powerful tool for life science researchers wanting nanoscale imaging and manipulation to study cells, molecules, and forces. At the first AFM BioMed conference, held in Barcelona, Spain, 19-21 April 2007, only 50 attendees were expected, but the response to the conference announcement was overwhelming: 220 researchers attended, with many of the pioneers in the development of AFM and of its use in biology giving talks. moreJul. 01, 2007
Time-of-Flight SIMS - Analysis in Life Sciences: In Life Sciences, chemical characterisation with Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) has found interest due to high surface sensitivity down to the femtomol range, and an information depth limited to the top-surface in the nanometer range, combined with molecular imaging capabilities in the micrometer range [1-3]. moreJan. 01, 2007
Atomic Force Microscopy for Bio-sensors Studies: Atomic Force Microscopy becomes an invaluable technique for the study of biological systems at a nanometric scale [1, 2]. During the past decade, it has been increasingly used to image and manipulate biomolecules and cell surfaces in air or in situ. Development of dynamic modes of operation adapted for the imaging of soft samples has significantly contributed to overcome the usual issue of damage done to these biological objects by the scanning tip .
Applications To Biology moreJan. 01, 2007
Controlled Light Exposure Microscopy (CLEM): Photobleaching and Phototoxicity Reduced - Photobleaching and phototoxicity are often the Achilles‘ heels of fluorescence live-cell imaging. Controlled Light Exposure Microscopy (CLEM) is a novel, simple imaging approach that reduces photobleaching and phototoxicity 2 to 10-fold without compromising image quality. The basic concept of CLEM is that light is only used where it is needed by spatial control (pixel by pixel) of the light exposure time. moreJan. 01, 2007
Z-stack Imaging Applications: Nano Focusing in Automated Microscopy - Advanced imaging microscopy often demands that images are collected with both speed and precision. Stepper motor driven focus mechanisms often do not meet the requirements essential to the success of the most demanding applications. New methods of automating the focus mechanism based on piezo drives offer a potential route to solve this problem. However it can be said that not all piezo drives were created equal, with certain formats offering far greater flexibility than others! moreJun. 01, 2006
Overview: Imaging & Microscopy 2/2006 (editorial).
Dear Reader, moreJun. 01, 2006
Sectioning Imaging Property (SIP) Charts - A Tool for Characterisation of Confocal Fluorescence Microscope Systems. Three-dimensional fluorescence microscopy has found widespread applications in recent years, especially in molecular cell biology.
Imaging in this type of microscopy is usually based on a series of sectioned images obtained by stepping the specimen through the focal region of a beam type scanning microscope. moreJun. 01, 2006
Core-Shell Nanoparticles: Imaging and Structure Determination of the Core and the Shell Regions. A method to produce nanoparticles with core-shell structure, having crystalline Ni3Si core and amorphous Si(O) shell is reported.
The core-shell nanoparticles are extracted from a two phase metallic alloys by selective phase separation using electrochemical dissolution technique. more