Aug. 12, 2010

Turn Up Brightness on Fluorescent Probes

Researchers from Carnegie Mellon University's Molecular Biosensor and Imaging Center (MBIC), USA are turning up the brightness on a group of fluorescent probes called fluoromodules that are used to monitor biological activities of individual proteins in real-time. This latest advance enhances their fluormodule technology by causing it to glow an order of magnitude brighter than typical fluorescent proteins. The new fluoromodules are five- to seven-times brighter than enhanced green fluorescent protein (EGFP), a development that will open new avenues for research. moreJul. 30, 2010

GPCR Biosensor

Researchers at Carnegie Mellon University have developed a new fluorescent biosensor that could aid in the development of an important class of drugs that target a crucial class of proteins called G protein-coupled receptors (GPCRs). more