Feb. 16, 2012
Leica Microsystems and APE, Berlin have developed a fully integrated confocal system with the capability for CARS (Coherent Anti-Stokes Raman Scattering) imaging, the Leica TCS CARS.
The microscope system is based on the Leica TCS SP5 II and benefits from imaging at video rate and a resolution of 8 x 8 Mpx for morphological studies.
moreOct. 18, 2011
Based on a novel proprietary technology, the InSight DeepSee delivers nearly double the tuning range of existing ultrafast lasers and provides seamless access to long infrared wavelengths for deepest in vivo imaging, taking multiphoton imaging to new depths.
moreJan. 18, 2011
Focus On Microscopy - FOM 2011: After the successful FOM2010 conference held in Shanghai, China in 2010, the next conference Focus on Microscopy 2011 takes place in Konstanz, Germany in the week before Easter from Sunday April 17 to Wednesday April 20, 2011. Hosted by the University of Konstanz, it starts around 6 o‘clock in the afternoon on Sunday the 17th with a plenary opening session followed by a welcome reception.
moreDec. 20, 2010
Optical spectroscopy offers multiple advantages over other identification techniques because it is highly sensitive to the biochemical nature of materials, can offer great spatial resolution when needed and can be made highly portable. This has made it the technique of choice for multiple applications ranging from remote sensing to disease diagnosis. For instance, needs in remote sensing in the atmosphere or in the battlefield have driven significant developments in devices and techniques using infrared and Raman spectroscopy [1, 2, 3].
moreOct. 18, 2010
A paper by researchers at the National Institute of Standards and Technology (NIST), USA may breathe new life into the use of a powerful-but tricky-diagnostic technique for cell biology. The paper appearing in the Biophysical Journal, demonstrates that with improved hardware and better signal processing, a powerful form of molecular vibration spectroscopy can quickly deliver detailed molecular maps of the contents of cells without damaging them.
moreSep. 20, 2010
Research that made it to the cover of the scientific journal Analytical Chemistry has shown that the detection method developed by researchers at the University of Twente's research institutes MESA+ and MIRA is even more sensitive than demonstrated earlier. Not only can it detect molecules accurately, it also shows the difference between them very clearly.
moreApr. 14, 2010
Newport's wavelength extension unit (WEU) is a turn key solution for various spectroscopy and microscopy applications. This device can be easily integrated with ultrafast light sources to perform CARS spectroscopy and CARS microscopy. It can also be integrated with two-photon microscopes to add CARS modality to enhance the imaging capabilities of microscopes. This wavelength extension unit uses a photonic crystal fiber to generate a broadband supercontinuum light source that can be used as the probe beam in pump probe spectroscopy, Stokes beam in CARS, etc., depending upon the application.
moreDec. 16, 2009
As coherent anti-Stokes Raman scattering microscopy (CARS) has migrated from physics labs into life-science labs, the demand for an easy-to-use, turnkey light source has increased. In response, High Q Laser and APE joined forces to develop a remote-controlled, truly hands-free single-box CARS light source-"picoEmerald"-which provides two tunable ultrafast-laser pulse trains from a single beam exit.
moreNov. 01, 2007
Wide-field CARS-Microscopy: Functional Imaging at a Glimpse. Coherent anti-Stokes Raman scattering (CARS) microscopy is a branch of nonlinear microscopy that allows chemical imaging of targeted vibrational transitions in unstained samples. A resonantly enhanced blueshifted CARS signal is generated from NIR or visible light, thus the method is more sensitive than normal Raman microscopy and offers better resolution than IR microscopy. CARS microscopes are mostly set up as confocal scanning microscopes, but wide-field approaches are possible as well.
moreNov. 01, 2007
Focus on Microscopy 2008: After the successful 2007 FOM conference this year in Valencia, Spain the next conference in the FOM series will take place in Osaka, Awaji Island, Japan from Sunday, April 13 to Wednesday, April 16, 2008. It will start around 6 o‘clock in the afternoon on Sunday the 13th with a plenary opening session followed by a welcome reception. The program schedule and general information of the conference can be found at the conference website: FocusOnMicroscopy.org.