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Monitoring Protein Molecules Using Gold Nanoparticles
Scientists at Johannes Gutenberg University Mainz (JGU) have developed a new method of observing individual proteins using gold nanoparticles. Detailed knowledge of the dynamics of proteins is necessary in order to understand the related biological processes that occur on the molecular level. To date, this information has been obtained by means of labeling proteins with fluorescent substances, but unfortunately this changes the proteins under investigation and thus influences the biological processes that are to be observed. more
Focused Ion Beam Microscopy: Deeper Insights into the Cell
Cryo-electron tomography provides high-resolution, three-dimensional insights into the cell. However, with this method only very small cells or thin peripheral regions of larger cells can be investigated directly. Scientists of the Max Planck Institute of Biochemistry (MPIB) in Martinsried, Germany have now developed a procedure to provide access to cellular regions which were previously nearly inaccessible.more
Studying Cell Adhesion with TIRF/AFM
Dr. Clemens Franz leads a group of researchers at the DFG-Center for Functional Nanostructures at Karlsruhe Institute of Technology (Germany) where he works on expanding the use of Atomic Force Microscopy (AFM) for cell biological applications. AFM has a strong advantage over other microscopy techniques. Samples can be imaged directly without prior preparation, such as staining or fixation. more
Transmission Electron Microscopy: Observing Cancer Cells in Action
Limitations in biomedical imaging technologies have hampered attempts to understand cellular and molecular behavior, with biologists trying to envision dynamic processes through static snapshots. Deborah Kelly , an assistant professor in the Virginia Tech Carilion Research Institute, has now developed a novel technology platform to peer closely into the world of cells and molecules within a native, liquid environment. more
UltraPath XVI - Conference on Diagnostic Electron Microscopy, Basic Research & Oncology
The 16th Meeting of the Society for Ultrastructural Pathology (UltraPath XVI) will be held on August 6-10, 2012 in the historical town of Regensburg, Germany. The Society was formed in 1986 with the mission to support and promote the application of electron microscopy in pathological diagnosis and research of human diseases. Over the years the scope of biennial meetings expanded and includes immunochemistry, molecular and cellular biology. more
FEI Launches MAPS Software for Cellular Biology Research
FEI has launched the MAPS (Modular Automated Processing System) software which combines the advantages of both light and electron microscopy for cellular biology research. more
Optically Measuring Single Cell Mass
The ability to measure single cell growth is of fundamental importance to our understanding of biological systems. Despite several major efforts, studying this phenomenon has remained largely intangible due to the simple fact that cells are small and only double their mass during their lifetime. In order to draw conclusions on growth trends and gain insight on growth regulatory systems, the required sensitivity to mass is in the order of femtograms.Introduction
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Lennart Nilsson Award 2011: The Secret Life of Cells – in Colour
The 2011 Lennart Nilsson Award is to be presented to American biologist Nancy Kedersha, who is to receive the prize for her colour pictures showing the inner life of a cell.The annual Lennart Nilsson Award is the world's most distinguished award in the field of scientific and medical photography, and is presented annually in honour of the legendary Swedish photographer. Like Lennart Nilsson, this year's recipient, Nancy Kedersha, has captured worlds that are otherwise hidden from human sight. She has rendered the invisible visible.
moreSep. 16, 2011
Living Lab for Cell Biology
FEI and Oregon Health & Science University (OHSU) announced a partnership to create the OHSU/FEI Living Lab for Cell Biology that will provide researchers with several state-of-the-art electron microscopes to advance the understanding and treatment of complex diseases such as cancer and AIDS.The OHSU/FEI Living Lab will be equipped with a variety of high-performance equipment including a Titan Krios transmission electron microscope (TEM) and a Helios NanoLab DualBeam. more
Spatial Light Interference Microscopy: Sheding Light on Cell Growth
Led by electrical and computer engineering professor Gabriel Popescu , the research team developed a new imaging method called spatial light interference microscopy (SLIM) that can measure cell mass using two beams of light. Described in the Proceedings of the National Academy of Science, the SLIM technique offers new insight into the much-debated problem of whether cells grow at a constant rate or exponentially. more- Legal
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