Apr. 17, 2012

Newport’s WEU-02 Wavelength Extension Unit for Multimodal Imaging

Newport's WEU-02 wavelength extension unit is designed to expand the capability of femtosecond lasers. Through a series of user controls, the WEU-02 can be configured for use in various spectroscopy, imaging, and pump-probe applications. It can also be integrated into two-photon microscope set-ups to add modalities for enhanced imaging capabilities. moreFeb. 16, 2012

Leica TCS CARS: First Confocal System With CARS Imaging

Leica Microsystems and APE, Berlin have developed a fully integrated confocal system with the capability for CARS (Coherent Anti-Stokes Raman Scattering) imaging, the Leica TCS CARS.
The microscope system is based on the Leica TCS SP5 II and benefits from imaging at video rate and a resolution of 8 x 8 Mpx for morphological studies. moreOct. 18, 2011

Spectra-Physics Pioneers New Ultrafast Laser for Deep Tissue Imaging

Based on a novel proprietary technology, the InSight DeepSee delivers nearly double the tuning range of existing ultrafast lasers and provides seamless access to long infrared wavelengths for deepest in vivo imaging, taking multiphoton imaging to new depths. moreJun. 10, 2011

Using Nanosecond Laser Pulses to Image Plaques Lining Arteries in 3D

Ji-Xin Cheng, associate professor of biomedical engineering and chemistry at Purdue University, and his research group have developed a new type of imaging technology to take precise three-dimensional images of plaques lining arteries. moreDec. 20, 2010

Vibrational Spectroscopy

Optical spectroscopy offers multiple advantages over other identification techniques because it is highly sensitive to the biochemical nature of materials, can offer great spatial resolution when needed and can be made highly portable. This has made it the technique of choice for multiple applications ranging from remote sensing to disease diagnosis. For instance, needs in remote sensing in the atmosphere or in the battlefield have driven significant developments in devices and techniques using infrared and Raman spectroscopy [1, 2, 3]. moreNov. 01, 2008

Wide-field CARS-Microscopy

Coherent anti-Stokes Raman scattering (CARS) microscopy is a branch of nonlinear microscopy that allows chemical imaging of targeted vibrational transitions in unstained samples. A resonantly enhanced blue-shifted CARS signal is generated from NIR or visible light, thus the method is more sensitive than normal Raman microscopy and offers better resolution than IR microscopy. CARS microscopes are mostly set up as confocal scanning microscopes, but wide-field approaches are possible as well.

Brief Introduction to CARS-microscopy
moreNov. 01, 2007

Wide-field CARS-Microscopy: Functional Imaging at a Glimpse

Wide-field CARS-Microscopy: Functional Imaging at a Glimpse. Coherent anti-Stokes Raman scattering (CARS) microscopy is a branch of nonlinear microscopy that allows chemical imaging of targeted vibrational transitions in unstained samples. A resonantly enhanced blueshifted CARS signal is generated from NIR or visible light, thus the method is more sensitive than normal Raman microscopy and offers better resolution than IR microscopy. CARS microscopes are mostly set up as confocal scanning microscopes, but wide-field approaches are possible as well. moreJul. 01, 2007

Harvard licensed Cars microscopy technology to Leica

Harvard licensed Cars microscopy technology to Leica: Harvard University's Office of Technology Development (OTD) and Leica Microsystems announced that Harvard has licensed its Cars microscopy technology to Leica for use in the company's confocal microscopes. The technology was developed in the lab of Xiaoliang Sunney Xie, Ph.D., Professor of Chemistry and Chemical Biology at Harvard. "This technology has far-reaching implications for helping advance important biomedical research," stated Isaac T. Kohlberg, Chief Technology Development Officer, Harvard University. more