Feb. 13, 2014
Leica Microsystems has introduced the Leica DCM8 for non-destructive three-dimensional surface profiling.
moreFeb. 07, 2014
Photonic Integrated Circuits (PIC) are hot candidates for being employed in the next generation of optical and quantum communication systems because of their promise regarding very high information transfer speed, robustness and the compatibility with standard microelectronics devices technology. Furthermore, the extremely high sensitivity of resonant nanophotonics structures to light-matter interactions makes them ideal for a new classes of sensors with a broad range of possible applications in physics, biology and chemistry.
moreJan. 24, 2014
The European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany offers a lot of different training courses in the field of microscopy.
moreDec. 30, 2013
Dichroics in highest level of performance are now available! They are manufactured by a special plasma coating technique, which results in a stress-free coating with fully dense dielectric films. Superflat dichroics with λ/10 specification after coating can be achieved on 2 mm substrates, no need of backside compensation or thick and expensive substrates. Typical applications are laser based spectroscopy methods like super-resolution microscopy, interferometry, TIRF microscopy, confocal microscopy etc.
moreNov. 25, 2013
A novel optical concept for a spinning disk confocal microscope is presented, which warrants maximal optical quality, speed and usability. It employs a single disk only instead of two, and it uses micromirrors instead of microlenses, thus minimizing chromatic aberrations and yielding an uncompromised performance over the full visible range from 405 - 700 nm. Careful optimization of coupling optics result in flat and homogenous illumination free of speckle artifacts, and the full optical performance is maintained over the full field of view.
moreSep. 24, 2013
Cancer cells metastasize in several stages - first by invading surrounding tissue, then by infiltrating and spreading via the circulatory system. Some circulating cells work their way out of the vascular network, eventually forming a secondary tumor. While the initial process by which cancer cells enter the bloodstream - called intravasation - is well characterized, how cells escape blood vessels to permeate other tissues and organs is less clear. This process, called extravasation, is a crucial step in cancer metastasis. Now researchers at MIT have developed a microfluidic device that mimics the flow of cancer cells through a system of blood vessels. Using high-resolution time-lapse imaging, the researchers captured the moments as a cancer cell squeezes its way through a blood vessel wall into the surrounding extracellular matrix. The process is "highly dynamic," as they write in a paper published in Integrative Biology; a better understanding of it may help scientists identify therapies to prevent metastasis.
moreAug. 20, 2013
Toptica's iChrome MLE is more than just the sum of four lasers in one box: it fully integrates different lasers and enhances them with unique features! The system delivers highest output powers up to 100 mW - from a single-mode polarization-maintaining fiber. All laser parameters can be conveniently operated via one control interface.
moreAug. 08, 2013
The International Symposium "Nanoscale Membrane Organisation" will take place in the hotel Vier Jahreszeiten, Schluchsse, Germany from October 24-25, 2013. Live cell imaging and confocal microscope techniques commonly used in the last 10 years have failed to resolve structures below the diffraction limit of 250 nm and therefore have missed many details of the nanoscale organization of membrane proteins. Recent technical developments and new concepts show that the plasma membrane is more highly organized at nanoscale distances than previously thought.
moreJun. 11, 2013
For excitable cells in which signaling events occur in milliseconds, a mathematical formalism for pixel-wise fitting generates virtually pixel noise-free image sequences from high-speed 2-dimensional confocal data. This approach provides novel insight into cardiac excitation-contraction coupling and its pathophysiology. Such an analytical approach can be extended into other biological systems to uncover otherwise inaccessible features of subcellular signal transduction in living cells.
moreDec. 18, 2012
Photonic Science Limited has introduced InGaAs cameras for the standard spectral range (900 to 1700nm) with extension in the visible range (400nm) as well as infrared region (2200nm).