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Correlative Microscopy

WITec and Tescan Introduce RISE Microscopy
Mar. 28, 2014

WITec and Tescan Introduce RISE Microscopy

WITec and Tescan have introduced RISE Microscopy, a correlative microscopy technique which combines confocal Raman Imaging and Scanning Electron (RISE) Microscopy within one integrated microscope system. more
RISE Microscopy
Mar. 27, 2014

RISE Microscopy

RISE Microscopy is a novel correlative microscopy technique that combines Scanning Electron Microscopy (SEM) and confocal Raman Imaging. Through RISE Microscopy ultra-structural surface properties can be linked to molecular compound information.
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Trends in Microscopy 2014
Mar. 11, 2014

Trends in Microscopy 2014

The conference "Trends in Micoscopy 2014" will take place from March 27 -29 in Freiburg, Germany. The conference brings together leading high-end microscope techniques developers and users from Germany with their world-wide colleagues.

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14th International ELMI Meeting
Jan. 06, 2014

14th International ELMI Meeting

The 14th European Light Microscopy Initiative (ELMI2014) conference will be held in Oslo, Norway from May 20-23, 2014. ELMI is an internationally recognized meeting on Light Microscopy and offers a unique combination of lectures, exhibitions and hands-on workshops organized by leading microscopy companies. The meeting is aimed at a life sciences audience and specifically focuses on close collaborative interactions between companies, developers and researchers. Imaging methods from a wide range of research fields will be presented that are relevant to both new and expert users of electronic and photonic methods.
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Multiscale and Multimodal Correlative Microscopy Workflows
Sep. 10, 2013

Multiscale and Multimodal Correlative Microscopy Workflows

The ability to efficiently and reliably locate and image an area of interest in a larger three dimensional sample remains a very challenging application in advanced microscopy. Approaches to address this issue include dedicated sample preparation steps to cut out the target area, or optical penetration using dedicated confocal systems. Both approaches are labor intense and cannot be automated easily. With X-ray microscopy, a new technology has evolved that shows a huge potential to bridge the gap between light and electron microscopy. more
Aug. 22, 2013

Correlative Microscopy: Specialized Endocytocis Consumes Membrane Tendrils

The process cells use to ‘swallow' up nutrients, hormones and other signals from their environment - called endocytosis - can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study, published in Nature Communications, could help explain how the cells on your skin become different from those that line your stomach or intestine.
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Two Microscopes Integrated in One
Aug. 01, 2013

Two Microscopes Integrated in One

A high-NA light microscope can be retro-fitted onto a Scanning Electron Microscope giving the possibility to perform simultaneous high-resolution fluorescence and electron microscopy on the same area of a sample. more
Microscopy Conference 2013
Jun. 19, 2013

Microscopy Conference 2013

It is a great pleasure to officially invite you to come and present your latest results at the Microscopy Conference 2013 in Regensburg, Germany. It will be held at the University of Regensburg, Germany, from August 25- 30, 2013. This conference follows the tradition of the "Dreiländertagung Mikroskopie". more
CLEM on Ultrathin Sections
Jun. 18, 2013

CLEM on Ultrathin Sections

Correlative light and electron microscopy (CLEM) combines the versatility of fluorescence microscopy (FLM) with the spatial resolution of transmission electron microscopy (TEM). For the analysis of tissues single resin or cryo-sections are incubated with fluorochrome- and gold-labeled probes. Areas of interest are selected at the FLM, and analyzed in the TEM at high resolution. This way, fluorescence is directly correlated to subcellular structures and/or corresponding immunogold signals.
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Targeted Subcellular Nanoanalysis
Apr. 16, 2013

Targeted Subcellular Nanoanalysis

We developed a new approach using cryo-correlative light and scanning transmission electron microscopy allowing analysis of targeted in situ intracellular ions and water measurements at the ultrastructural level within domains identified by examination of specific GFP-tagged proteins [1]. We illustrate the potential of this approach by investigating changes in water and ion content in nuclear domains identified by GFP-tagged proteins in cells stressed by Actinomycin D treatment and controls. more
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