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Fluorescence Imaging

Multi Color Laser Light Source for Super Resolution Microscopy
Nov. 15, 2011

Multi Color Laser Light Source for Super Resolution Microscopy

The Agilent Monolithic Laser Combiner MLC 400, distributed by Laser 2000 Europe, is a perfect solution for confocal, super resolution and fluorescence microscopy. Long-life DPSS and diode lasers are efficiently combined in a single output fiber, which is coupled to the microscope. With the integrated AOTF fast switching between the wavelengths and fast regulation of the output power is possible.
The unique design includes permanent factory alignment. No more losing time with adjusting lasers instead of taking microscope images. more
Spectra-Physics Pioneers New Ultrafast Laser for Deep Tissue Imaging
Oct. 18, 2011

Spectra-Physics Pioneers New Ultrafast Laser for Deep Tissue Imaging

Based on a novel proprietary technology, the InSight DeepSee delivers nearly double the tuning range of existing ultrafast lasers and provides seamless access to long infrared wavelengths for deepest in vivo imaging, taking multiphoton imaging to new depths. more
Consistent Isolation and Fluorescence Imaging of Individual Atoms
Aug. 04, 2011

Consistent Isolation and Fluorescence Imaging of Individual Atoms

We describe new methods to consistently isolate and image individual atoms. We isolate one atom by inducing inelastic light assisted collisions in a group of atoms held in optical tweezers. Each atom pair that undergoes a collision gains enough energy for only one of the atoms to leave the optical tweezers, leading to a single atom remaining. This atom is imaged using fluorescence microscopy. more
PicoQuant Image Contest
Mar. 09, 2011

PicoQuant Image Contest

PicoQuant has invited all users of PicoQuant microscope or spectrometer to enter the image contest:
All techniques of Time-Correlated Single Photon Counting and related methods are acceptable in this contest, e.g. fluorescence imaging, pulsed excitation, laser ablation, nanosurgery or micromanipulation. All approved entries will be presented in the PicoQuant Application Gallery on the company's website. Whether tissue, organisms, single molecules or nanocrystals, any type of specimen is imaginable. more
NanoSight: NS200 Nanoparticle Characterization System Will be Launched at Pittcon
Feb. 24, 2011

NanoSight: NS200 Nanoparticle Characterization System Will be Launched at Pittcon

NanoSight will introduce NS200 nanoparticle characterization system at Pittcon 2011:
N200 is easy to use, has an optional blue laser to improve imaging capability, and fluorescence filters can be added when working with suitably labeled particles. Furthermore, the laser is triggered to reduce thermal issues with respect to the sample, restricting photobleaching during fluorescence imaging.   more
Simple Solution for Long Term Live Cell Imaging
Jun. 18, 2010

Simple Solution for Long Term Live Cell Imaging

The new BioStation IM-Q allows users with minimal microscopy experience to conduct live cell imaging without a steep learning curve. This compact system incorporates a microscope, an incubator and a high sensitivity, cooled quantitative CCD camera integrated into a single package. Providing a stable environment for live cells and advanced phase and fluorescence imaging solutions for simple, long term, cell friendly timelapse data acquisition, the BioStation IM-Q eliminates the need for a darkroom. It can be installed anywhere. more
May. 03, 2010

Marking Brain Tumors

Researchers have developed a way to enhance how brain tumors appear in MRI scans and during surgery, making the tumors easier for surgeons to identify and remove. Scientists at Ohio State University, USA are experimenting with different nanoparticles that they hope may one day be injected into the blood of patients and help surgeons remove lethal brain tumors known as glioblastomas. In the journal Nanotechnology, researchers reported that they have manufactured a small particle called a nanocomposite that is both magnetic and fluorescent. more
Fluorescent Compounds Make Tumors Glow
Apr. 30, 2010

Fluorescent Compounds Make Tumors Glow

A series of novel imaging agents could light up tumors as they begin to form - before they turn deadly - and signal their transition to aggressive cancers. The compounds - fluorescent inhibitors of the enzyme cyclooxygenase-2 (COX-2) - could have broad applications for detecting tumors earlier, monitoring a tumor's transition from pre-malignancy to more aggressive growth, and defining tumor margins during surgical removal. COX-2 is an attractive target for molecular imaging. It's not found in most normal tissues, and then it is "turned on" in inflammatory lesions and tumors. more
Ultrasensitive Imaging Method
Apr. 14, 2010

Ultrasensitive Imaging Method

New research findings suggest that an experimental ultrasensitive medical imaging technique that uses a pulsed laser and tiny metallic "nanocages" might enable both the early detection and treatment of disease. The system works by shining near-infrared laser pulses through the skin to detect hollow nanocages and solid nanoparticles - made of an alloy of gold and silver - that are injected into the bloodstream. more
Laser Fluorescence Filters
Feb. 19, 2010

Laser Fluorescence Filters

A collaboration between Cobolt and Semrock, has resulted in the development of optical filters optimized for use with the Cobolt Mambo 594 nm orange laser in fluorescence instrumentation. To realize the benefits of this new laser wavelength, optical filters that are designed with matched spectral properties are needed. Semrock has announced a number of new filters designed specifically for instrumentation based on the 594 nm laser, and ideal for excitation and detection of Texas Red, Alexa Fluor 594, and the popular new fluorescent proteins mCherry and mKate. more
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