Jan. 27, 2012

iXon Ultra from Andor: EMCCD Camera Now Over 60 Percent Faster

The iXon Ultra high-performance EMCCD camera from Andor Technology represents the next generation of the iXon platform.
Key Specifications
◦ Active Pixels 512 x 512
◦ Pixel Size 16 x 16 µm
◦ Image Area 8.2 mm x 8.2 mm 
◦ Image Area pixel well depth 160,000 e-
◦ Readout Rate 17 MHz
◦ Max. Frame Rate 56 fps
◦ Read Noise < 1 e- with EM gain
◦ QEmax > 90% moreJan. 05, 2012

Focus On Microscopy 2012

After the successful FOM2011 conference held in Konstanz this year, Focus on Microscopy 2012 (FOM2012) will be held in Singapore. It will take place in the week before Easter from Sunday April 1 to Wednesday April 4, 2012 at the Suntec Singapore International Convention & Exhibition Centre in the heart of the city. It is sponsored by the National University of Singapore (NUS), the Nanyang Technological University (NTU), the Centre of Bioimaging Sciences (CBIS), and the Mechanobiology Institute (MBI). moreDec. 13, 2011

sCMOS Camera With High Sensitivity, High Resolution and Fast Readout

Hamamatsu Photonics introduces the world's first   Gen II sCMOS camera, the ORCA-Flash4.0.  It simultaneously provides high sensitivity (over 70% QE at 600 nm), very low noise (1.3 electrons), and fast frame rates (100 frames/s).
This versatile camera is suitable for many applications including super-resolution microscopy, TIRF microscopy and FRET. moreNov. 15, 2011

Dual Wavelength Imaging – The Ultimate Solution

The ORCA-D2 CCD camera is designed around two ER-150 CCD devices.  It can capture simultaneous dual wavelength or multiple focal plane images.  Each CCD captures a field of view measuring 1280 (H) x 960 (V) pixels, and each CCD has independent exposure and gain settings to accommodate significantly different intensity levels between the two images as is often seen in FRET and ratio imaging applications.   moreNov. 15, 2011

Multi Color Laser Light Source for Super Resolution Microscopy

The Agilent Monolithic Laser Combiner MLC 400, distributed by Laser 2000 Europe, is a perfect solution for confocal, super resolution and fluorescence microscopy. Long-life DPSS and diode lasers are efficiently combined in a single output fiber, which is coupled to the microscope. With the integrated AOTF fast switching between the wavelengths and fast regulation of the output power is possible.
The unique design includes permanent factory alignment. No more losing time with adjusting lasers instead of taking microscope images. moreAug. 29, 2011

Measuring Nanodistances in Cells

Understanding how complex processes such as receptor signal transduction work in cells requires knowledge of the structure-function relationships underlying the composition of protein complexes. Characterization of the oligomerization state of complexes requires the measurement of distances around 10-15 nm, too long for fluorescence energy transfer (FRET), but too small for optical resolution. Here we discuss various approaches that are being taken to mea­sure these distances in cells.

Spatial Resolution Requirements for Cell Biology
moreJul. 28, 2011

Quantaurus-Tau from Hamamatsu: Fluorescence Lifetime Measurement With Single-Photon-Counting ...

Quantaurus-Tau from Hamamatsu Photonics is a compact, easy-to use system for measuring the fluorescence lifetime of photoluminescent materials in thin film, powder, solid, or liquid form from sub-nanoseconds to the millisecond range, with single-photon-counting sensitivity. moreApr. 13, 2011

"Jumping Dye": Single-molecule Four-colour FRET

To control light on the nano scale, scientists require new kinds of optical devices to function as wires and switches. The energy transfer between single dye molecules, for instance, could function as a sort of wire. There is already an example in nature for such a transfer mode: during the process of photosynthesis, light energy is transported between single molecules within the light harvesting complexes. moreMar. 04, 2011

Andor Introduces a Two Camera Imaging Adapter

Andor Technology has launched TuCam, a high performance, two-camera adapter for macro or microscopic imaging applications.

TuCam can be configured for simultaneous imaging from two similar cameras or as a switch between camera models with different imaging capabilities. The solution is particularly suited for the detection of two different fluorophores in experiments such as co-localization FRET or ratiometric ion signalling. moreFeb. 14, 2011

SymPhoTime Software Version 5.2.4 from PicoQuant

PicoQuant introduced version 5.2.4 of the fluorescence lifetime imaging and correlation software SymPhoTime along with a new discussion forum. more