Jan. 04, 2010

Embryonic Stem Cells Morphology

Morphological characterisation of embryonic stem cells is important in many ways. In culture, the morphology indicates the status of the cells, e.g., undifferentiated or differentiated, and also provides clues about the general health and condition of the cells, e.g, apoptotic, necrotic or mycoplasma contaminated. While there are a vast range of studies characterising stem cell markers by light microscopy, there is limited information about the fine structure of hES cells and colonies by electron microscopy. more