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A Perfect Match
Feb. 27, 2015

A Perfect Match

Capturing and documenting a true-to-life representation of your sample is an important aspect of microscopy, achieved using the digital camera. Digital cameras specialized for microscopy come in all shapes and sizes, and selecting the best camera for your system can be a daunting task. It can be of help to consider four main features that essentially dictate camera performance: color reproduction, sensitivity, live image quality and resolution. Being aware of what these parameters really mean for your chosen application will guide you to a camera to complete your microscope system and truly enhance your experience.
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ELMI Meeting 2015
Jan. 16, 2015

ELMI Meeting 2015


The annual Meeting of the European Light Microscopy Initiative (ELMI) is an internationally recognized meeting on Light Microscopy and a unique blend of lectures and hands-on workshops on the newest microscopy research and techniques aimed at a life sciences audience. In 2015 it will take place near Barcelona, Spain, from the 19th to the 22nd of May in the small coastal village of Sitges. The location of the meeting will be a spacious resort with a fully developed conference infrastructure, the Melia Sitges Hotel.
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Highest Resolution Ever with X-Ray Microscopy
Sep. 19, 2014

Highest Resolution Ever with X-Ray Microscopy

A record-setting X-ray microscopy experiment may have ushered in a new era for nanoscale imaging. Working at the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab), a collaboration of researchers used low energy or "soft" X-rays to image structures only five nanometres in size. This resolution, obtained at Berkeley Lab´s Advanced Light Source (ALS), a DOE Office of Science User Facility, is the highest ever achieved with X-ray microscopy.
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Neurobiology: Molecular Learning Machines Under the Microscope
Aug. 27, 2014

Neurobiology: Molecular Learning Machines Under the Microscope

Neurotransmitters play an important role in the communication of nerve cells. Major details of the processes involved have been unclear until recently. Scientists of the University of Würzburg have now shed light on these processes by using a new technique. more
Lasers Makes Atomic Force Microscopes Way Cooler
Aug. 25, 2014

Lasers Makes Atomic Force Microscopes Way Cooler

Laser physicists have found a way to make atomic-force microscope probes 20 times more sensitive and capable of detecting forces as small as the weight of an individual virus. The technique, developed by researchers at The Australian National University (ANU), hinges on using laser beams to cool a nanowire probe to minus 265 degrees Celsius. more
Airyscanning
Aug. 24, 2014

Airyscanning

Confocal laser scanning microscopes (CLMs) are renowned for their sectioning capability. This feature is enabled by the use of pinhole, which rejects out-of-focus light. Less appreciated, on the other hand, is the gain in lateral resolution by this type of microscopes for one obvious reason. more
COIN: The Combined Nanoscopy Technique
Aug. 20, 2014

COIN: The Combined Nanoscopy Technique

COIN: Göttingen Scientists develop a combined technique for studying cellular structures via high-resolution imaging. more
Super-Resolution Microscopy
Aug. 07, 2014

Super-Resolution Microscopy

In the year 2008 Nature Methods has selected super-resolution microscopy or nanoscopy as "method of the year" [1]. Since that time super-resolution microscopy has emerged from specialized physics laboratories and become a powerful tool for biologists. The field of application is constantly growing and since recently even expanding in the axial dimension for single molecule localization microscopy. The process to get high quality super-resolution images can be divided in three important steps: sample preparation, image acquisition and image processing. Especially the first step has to be considered with a lot of care, since higher resolving power demands more stringent sample preparation.
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Correlative Light and Electron Microscopy
Jun. 30, 2014

Correlative Light and Electron Microscopy

Robust sample preparation is key to any multiuser, high-end electron microscopy facility. At the EMBL our facility is permanently hosting 10 to 15 projects in parallel, and provides service to approximately 50 users per year. Each of these users face a number of different challenges when it comes to sample preparation and have different levels of experience. Our goal is to assist by standardizing methods and developing a toolbox to help projects become feasible and more efficient.
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Jun. 26, 2014

CLARITY: Seeing the Inner Workings of the Brain

Bio-X scientists have improved on their original technique for peering into the intact brain, making it more reliable and safer. The results could help scientists unravel the inner connections of how thoughts, memories or diseases arise. more
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