Jul. 17, 2013
NKT´s SuperK Extend-UV wavelength extension unit provides tunable light in the entire 270-400nm range with power levels on the order of 10-100 μW.
moreJul. 12, 2013
Available on the iXon Ultra 897 camera, the Optically Centred Crop Mode offers extremely fast frame rate performance from Region of Interest (ROI), and is ideally matched to the speed and sensitivity needs of live cell super-resolution microscopy.
moreJun. 08, 2013
The symposium "Seeing is Believing - Imaging the Processes of Life" will take place at the EMBL Advanced Training Centre, Heidelberg, Germany from October 3 - 6, 2013. With the symposium we aim to bring together the leading developers of imaging methods with cutting edge applications that illustrate how imaging can answer biological questions. We will place emphasis on methods that are able to capture the dynamics of life and aim to span the whole range from molecular resolution to imaging of whole organisms.
moreMay. 13, 2013
Fluorescence microscopy assumed a pivotal role in cell biology once it was possible to stain cell components selectively by fluorescing dyes. One of the first explorers of targeted stainings, Paul Ehrlich, had the idea that something that stains specifically should also kill specifically - which was associated with the term "magic bullet", the essential idea of chemotherapy. His group discovered Salvarsan, a tailored drug against syphilis - though not specific enough not to cause substantial side effects.
moreApr. 02, 2013
The development of nanostructured lacquers and propellants needs to master the cellulose nitrate processing on the nanoscale. The challenge is the deposition of single cellulose nitrate molecules to image them with molecular resolution. We report on the effect of solvent, shaking duration and deposition techniques, from which the spray technique succeeded, for the first time to our knowledge, to image by Atomic Force Microscopy, individual molecular cellulose nitrate polymeric chains.
moreMar. 25, 2013
We show identification of chemical compounds and chemical maps at 20 nm resolution, enabled by a novel combination of infrared spectroscopy and near-field microscopy. Nano-FTIR returns the surface topography and simultaneously the local mid-infrared spectrum of the tiny volume (20 nm3) just below the probing tip thus allowing correlative topography/hyperspectral infrared images. In the case of molecular substances, comparison with common infrared databases enables local chemical recognition.
moreMar. 18, 2013
We developed a new ultramicroscopy design equipped with modified optics to achieve 3D-vizualizations of specimens with μm-resolution. The optical unit consists of elements with complex surface structures to create an ultra-thin light sheet. Diffraction and other unwanted optical effects are minimized, while the laser energy is used more efficiently. This enables us to obtain marked enhancements in resolving fine details of specimens (e.g. fruit-flies, entire mouse brains, and mouse hippocampi).
moreDec. 13, 2012
Variable Pressure Scanning Electron Microscopy (VP-SEM) has become an important tool for the imaging of hydrated specimens and samples with low conductivity. This article outlines various research scenarios where VP-SEM allowed minimal sample processing that often enabled successive specimen reuse. We present cases where these characteristics allowed imaging of specimens otherwise impossible using conventional SEM methods.
moreSep. 10, 2012
This completely revised successor to the Handbook of Microscopy supplies in-depth coverage of all imaging technologies from the optical to the electron and scanning techniques. Adopting a twofold approach, the book firstly presents the various technologies as such, before going on to cover the materials class by class, analyzing how the different imaging methods can be successfully applied.
moreFeb. 17, 2012
Andor Technology has announced that they come together with Molecular Devices to integrate the imaging software solution Metamorph NX in Andor´s confocal imaging unit Revolution DSD.