Apr. 07, 2015
Photoacoustic Computed Microscopy (PACM) is a new label-free microscopic method that combines current photoacoustic microscopy technique with a model-based inverse reconstruction algorithm to provide functional images of microvasculature. This article demonstrates its in vivo imaging ability of quantifying important functional parameters at the small vessel level in a rodent model. This new technique offers a unique tool for neuroscience research and for visualizing microvasculature dynamics.
moreFeb. 26, 2015
The 12th Multinational Congress on Microscopy (MCM2015) will take place from 23-28 August, 2015 in Eger, Hungary. The aim of MCM conferences is to bring together leading experts and emerging young researchers applying many types of microscopic techniques in the field of life or material sciences as well as provide a forum for new directions.
moreFeb. 03, 2015
In a Petri dish culture, cells and tissue are sufficiently transparent that they can be readily explored using any of a variety of microscopy techniques. Whole organs, however, are opaque under light microscopy, and it has proved challenging to find a way to clarify tissue to the extent needed to permit microscope observations of individual cells deep inside an animal. A research team led by Hiroki Ueda and Kazuki Tainaka from the Laboratory for Synthetic Biology at the RIKEN Quantitative Biology Center has now developed a remarkably effective tissue-clearing technique that promises to allow direct microscopy studies of deep tissue in organs and even whole animals. Results were published in Cell.
moreJan. 16, 2015
The annual Meeting of the European Light Microscopy Initiative (ELMI) is an internationally recognized meeting on Light Microscopy and a unique blend of lectures and hands-on workshops on the newest microscopy research and techniques aimed at a life sciences audience. In 2015 it will take place near Barcelona, Spain, from the 19th to the 22nd of May in the small coastal village of Sitges. The location of the meeting will be a spacious resort with a fully developed conference infrastructure, the Melia Sitges Hotel.
moreJan. 13, 2015
January 20, 2015, the deadline for abstract submission for the FOM2015 Goettingen conference is nearing. Please submit your abstract by this date.
Abstracts for oral and poster presentations can be submitted through the conference website, where also the conference registration has opened and hotel information is available.
moreJan. 02, 2015
mmc2015 will be one of Europe's largest conference and exhibition dedicated to microscopy and imaging and will take place from June 29 - July 2, 2015 in Manchester, UK. For the first time the mmc series will incorporate EMAG, providing an unprecedented opportunity to present your work to an audience that will include the biggest and brightest names in both the life and physical sciences, and in light and electron microscopy.
moreNov. 19, 2014
After the successful FOM2014 conference held in Sydney, Australia this year, it is a pleasure to announce FOM2015, the next Focus on Microscopy conference. It will take place in Göttingen, Germany in the week before Easter from Sunday March 29 to Wednesday April 1, 2015. Focus on Microscopy 2015 is the continuation of a yearly interdisciplinary conference series running now for well over two decades. It presents the latest innovations and new trends in multi-dimensional light microscopy, super-resolution and image processing together with their application in biology, medicine and material sciences.
moreNov. 11, 2014
Third Harmonic Generation (THG) microscopy is a non-fluorescent multi-photon technique that combines the advantages of label-free imaging with restriction of signal generation to the focal spot of the scanning laser. It allows three-dimensional imaging of refraction index mismatches and of hemoglobin. We applied it to image mouse tissues and to characterize blood vessels and blood flow velocity. In small arteries, THG line scanning reveals the pulse velocity curve and hence the heart rate.
moreOct. 27, 2014
Cell-derived membrane vesicles (MVs) that are released in body fluids, like blood or saliva, are potential biomarkers for diseases, such as cancer. Techniques capable of measuring MV properties, like size and concentration, directly in biofluids are thus needed. We developed a microfluidic chip with integrated light sheet illumination, and used it to perform fluorescence Single Particle Tracking (fSPT) size and concentration measurements of MVs in human tumor interstitial fluid.
moreOct. 08, 2014
For a long time optical microscopy was held back by a presumed limitation: that it would never obtain a better resolution than half the wavelength of light. Helped by fluorescent molecules the Nobel Laureates in Chemistry 2014 ingeniously circumvented this limitation. Their ground-breaking work has brought optical microscopy into the nanodimension.