Feb. 02, 2012

Transmission Electron Microscopy: Observing Cancer Cells in Action

Limitations in biomedical imaging technologies have hampered attempts to understand cellular and molecular behavior, with biologists trying to envision dynamic processes through static snapshots. Deborah Kelly , an assistant professor in the Virginia Tech Carilion Research Institute, has now developed a novel technology platform to peer closely into the world of cells and molecules within a native, liquid environment. moreJan. 17, 2012

sCMOS Camera With High Sensitivity, High Resolution and Fast Readout

Hamamatsu Photonics introduces the world's first Gen II sCMOS camera, the ORCA-Flash4.0.  It simultaneously provides high sensitivity (over 70% QE at 600 nm), very low noise (1.3 electrons), and fast frame rates (100 frames/s). This versatile camera is suitable for many applications including super-resolution microscopy, TIRF microscopy and FRET. moreDec. 13, 2011

sCMOS Camera With High Sensitivity, High Resolution and Fast Readout

Hamamatsu Photonics introduces the world's first   Gen II sCMOS camera, the ORCA-Flash4.0.  It simultaneously provides high sensitivity (over 70% QE at 600 nm), very low noise (1.3 electrons), and fast frame rates (100 frames/s).
This versatile camera is suitable for many applications including super-resolution microscopy, TIRF microscopy and FRET. moreNov. 14, 2011

Nikon Announces NIS-Elements Software Upgrade

Nikon has announced the availability of version 4.0 of NIS-Elements. Version 4.0 offers the ability to control current existing and the latest Nikon systems, ensuring familiarity on all Nikon imaging platforms.
New Features
◦ Over 100 new functions for improved user experience
◦ New support for third party cameras and hardware
◦ Easier switching between microscope applications
◦ Improved user rights management moreNov. 11, 2011

Mad City Labs Releases Nano-Cyte LC

Mad City Labs has released Nano-Cyte LC, a complete image acquisition and stabilization instrument for live cell imaging.
With Nano-Cyte LC, temperature gradients and microscope drift are no longer a problem. The integrated approach to image stabilization yields image stability within ±10 nanometers in X and Y, and ± 20 nanometers in Z. moreSep. 26, 2011

A New Twist to Quantum Dot Tracking - New Nanoparticle Changes Color Continuously

There are three issues, all of which are related to blinking, in quantum dot-based particle/molecule tracking. The recently reported "non-blinking quantum dots" address only one of the three issues. Here we report a new class of quantum dot-based composite nanoparticles that emit fluorescence with continuous intensity and alternating color, effectively addressing all three blinking-related issues, as well as providing greatly enhanced brightness compared with single quantum dots. moreSep. 23, 2011

Andor Introduces Differential Spinning Disk Uni

Andor Technology has introduced the Differential Spinning Disk (DSD) Uni. The DSD Uni brings with it the ability to add a confocal unit to almost any fluorescence microscope, upright or inverted, irrespective of manufacturer. moreAug. 29, 2011

Spatial Light Interference Microscopy: Sheding Light on Cell Growth

Led by electrical and computer engineering professor Gabriel Popescu , the research team developed a new imaging method called spatial light interference microscopy (SLIM) that can measure cell mass using two beams of light. Described in the Proceedings of the National Academy of Science, the SLIM technique offers new insight into the much-debated problem of whether cells grow at a constant rate or exponentially. moreAug. 27, 2011

Raman Spectroscopy: Highly Sensitive Probes for Cancer Diagnostics

Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for detecting and analyzing chemicals. The technology has recently emerged as a non-invasive tool for imaging cells and detecting cancer. Compared with fluorescence microscopy and other conventional fluorescence-based imaging techniques, SERS does not suffer from the problem of photobleaching-degradation of the fluorescence of the probes used as a result of repeated light exposure. moreAug. 15, 2011

Combining Light-sheet Microscopy and Single Molecule Spectroscopy

Researchers can now watch molecules move in living cells, literally millisecond by millisecond, thanks to a new microscope developed by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Published online in Nature Biotechnology, the new technique provides insights into processes that were so far invisible.
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