Dec. 13, 2013
The National Physical Laboratory (NPL) has just initiated a project, '3D nanoSIMS - world beating label-free molecular imaging', which could revolutionise medicines research. Working with major pharmaceutical company GlaxoSmithKline, the project team is designing an instrument which could go beyond the micrometre resolution imaging currently available, by developing a 3D label-free molecular imaging system with nanometric spatial resolution.
moreJan. 10, 2013
The 8th annual meeting of the European Society for Molecular Imaging (ESMI) will take place from 26-28 May 2013 in Torino, Italy. Molecular imaging is rapidly moving to multimodality approaches, integrating nuclear, radiological and microscopic imaging. To acknowledge this trend, the ESMI strives to integrate the themes of in vivo and molecular microscopy into existing activities of molecular imaging. Novel avenues we recognize include intravital microscopy of disease processes in live animals, fluorescence-guided surgery, and endoscopic detection of diseased tissue.
moreMar. 29, 2012
The MicroProbe Objective (MPO) lenses from Olympus are especially suited for studying the internal biology of living organisms.
The two water-immersion lenses, namely the 27x magnification IV-OB35F22W20 and the 20x IV-OB13F20W20, have an needle-like design, with the lenses housed in tips measuring 3.5 mm and 1.3 mm in diameter. This means they can be inserted into very small surgical excisions, facilitating in vivo imaging without significantly disrupting the natural state of the tissue or organ being investigated.
moreSep. 26, 2011
There are three issues, all of which are related to blinking, in quantum dot-based particle/molecule tracking. The recently reported "non-blinking quantum dots" address only one of the three issues. Here we report a new class of quantum dot-based composite nanoparticles that emit fluorescence with continuous intensity and alternating color, effectively addressing all three blinking-related issues, as well as providing greatly enhanced brightness compared with single quantum dots.
moreJan. 17, 2011
A group of researchers at Universidad Carlos III de Madrid (UC3M) have designed and developed a biomedical scanner that detects cellular processes at the molecular level and indicates malfunctioning of an organ before said malfunction can produce an anatomical change.
moreDec. 07, 2010
The new technique is based on stimulated Raman scattering, a complementary partner to MRI. Pictured are structural components of tissue - lipids (red), proteins (green), and water (blue). The images show a sebaceous gland wrapping around a hair in the viable epidermis of mouse skin.
A novel type of biomedical imaging, made possible by new advances in microscopy from scientists at Harvard University, is so fast and sensitive it can capture "video" of blood cells squeezing through capillaries.
moreJul. 01, 2007
7th International ELMI Meeting: Light Microscopy, complementing the systematic approaches of molecular genetics, has become one of the most powerful and important tools for modern biomedical research. Focused on the progress in this sparkling field, this years ELMI (European Light Microscopy Initiative) meeting was held at the unexpectedly sunny National Science learning Centre on the University of York campus between 17-20 April.
moreJul. 01, 2007
Time-of-Flight SIMS - Analysis in Life Sciences: In Life Sciences, chemical characterisation with Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) has found interest due to high surface sensitivity down to the femtomol range, and an information depth limited to the top-surface in the nanometer range, combined with molecular imaging capabilities in the micrometer range [1-3].