Aug. 28, 2012
A team of Italian researchers has performed a sight-correcting feat for a microscope imaging technique designed to explore the neural pathways of the brain. The researchers combined the advantages of light sheet illumination with confocal microscopy and called their new technique confocal light sheet microscopy (CLSM). The images obtained with CLSM, Francesco Pavone says, are 100 percent sharper than those acquired with conventional light-sheet based microscopy.
moreJun. 15, 2012
Andor Technology has launched the Revolution XD spinning disk confocal family, a flexible system solutions focused on live cell high speed imaging.
moreApr. 04, 2012
A challenge in neuroscience research is to understand the mechanisms underlying synapse formation and how nerve cells contact each other to transmit information.
Most excitatory synapses in the brain are built on actin-rich dendritic protrusions called spines and, as numerous psychiatric and neurological diseases are accompanied by alterations of spine numbers or size, the elucidation of mechanisms that regulate formation and plasticity of spinous synapses is vital.
moreMar. 02, 2012
How do real neural networks, composed of numerous different types of neurons, interconnected by complex arrangements of synapses, process information? Randy M. Bruno, Ph.D., Assistant Professor at the Department of Neuroscience, Columbia University, NY, USA is pursuing this question using the rodent whisker-barrel system. Here, anatomically and functionally distinct networks - barrels and barrel columns - are clearly identifiable, and the sensory transducers that provide input are directly controllable.
moreFeb. 16, 2012
Leica Microsystems and APE, Berlin have developed a fully integrated confocal system with the capability for CARS (Coherent Anti-Stokes Raman Scattering) imaging, the Leica TCS CARS.
The microscope system is based on the Leica TCS SP5 II and benefits from imaging at video rate and a resolution of 8 x 8 Mpx for morphological studies.
moreFeb. 09, 2012
Using the STED microscopy developed by Stefan Hell, researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen, Germany have, for the first time, managed to record detailed live images inside the brain of a living mouse. Captured in the previously impossible resolution of less than 70 nanometers, these images have made the minute structures visible which allow nerve cells to communicate with each other.
moreNov. 16, 2011
Nikon has launched the Eclipse Ni series. This upright research microscope series offers multi-mode system expandability to meet the imaging needs of bioscience and medical research on one platform.
moreAug. 11, 2011
Is the cause of diseases such as Alzheimer‘s, epilepsy and schizophrenia rooted in a deficiency or rise in chemical messengers? The „Functional Cell Biology" working group at the Charité University Hospital‘s Institute for Integrative Neuroanatomy in Berlin is looking into this and similar issues. The results are forming the basis of a fundamental understanding of the diseases and are intended to provide indications for therapeutic approaches. Researchers are employing the latest imaging and image analysis techniques and methods in the course of their investigations.
moreJul. 29, 2011
Stephanie Meyer, a physicist specializing in optics, is bringing new capabilities to the University of Colorado Denver Anschutz Medical Campus by building an advanced, super-resolution microscope able to see some of the innermost workings of the cell.
moreJul. 28, 2011
The development of new methods for imaging living cells with nanometric resolution is one of the most addresses topics in modern biology. Atomic force microscopy (AFM) provides an unpaired resolution in the out of plane z coordinate, - often around 1nm and even better -, and in the xy plane about 10nm and less.