Jun. 26, 2014
Bio-X scientists have improved on their original technique for peering into the intact brain, making it more reliable and safer. The results could help scientists unravel the inner connections of how thoughts, memories or diseases arise.
moreJun. 02, 2014
Synapses are the contacts between nerve cells that allow the flow of information that makes our brains work. However, the molecular architecture of these highly complex structures has been unknown until now. A research team from Göttingen, led by Prof. Silvio O. Rizzoli from the DFG Research Center and Cluster of Excel-lence Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB) of the University Medical Center Göttingen, managed to determine the copy numbers and positions of all important building blocks of a synapse for the first time.
moreSep. 10, 2013
Scientists at the Campus Vienna Biocenter (Austria) have found a way to overcome some of the limitations of light microscopy. Applying the new technique, they can record the activity of a worm's brain with high temporal and spatial resolution, ultimately linking brain anatomy to brain function. The journal Nature Methods publishes the details in its current issue.
moreAug. 22, 2013
A combination of devices for light and electron microscopy has been installed in the Neurobiology Centre of the Nencki Institute, Warsaw, Poland. This equipment will soon be applied by researchers to better understand the structure, function and capabilities of the human brain.
moreJun. 27, 2013
BigBrain: A new three-dimensional model of the brain now provides in-depth insights into the human control centre. It allows us to see and understand the complicated structure of the brain on a microscopic level in all three spatial dimensions for the first time. This is made possible using images with a resolution of 20 micrometres - the size of a neuron, or less than half the diameter of a human hair. Jülich researchers headed by neuroscientist Prof. Dr. Katrin Amunts and their colleagues from Montreal (Canada) have worked on the freely accessible model for five years. Their findings were published in the journal Science.
moreAug. 28, 2012
A team of Italian researchers has performed a sight-correcting feat for a microscope imaging technique designed to explore the neural pathways of the brain. The researchers combined the advantages of light sheet illumination with confocal microscopy and called their new technique confocal light sheet microscopy (CLSM). The images obtained with CLSM, Francesco Pavone says, are 100 percent sharper than those acquired with conventional light-sheet based microscopy.
moreJun. 15, 2012
Andor Technology has launched the Revolution XD spinning disk confocal family, a flexible system solutions focused on live cell high speed imaging.
moreApr. 04, 2012
A challenge in neuroscience research is to understand the mechanisms underlying synapse formation and how nerve cells contact each other to transmit information.
Most excitatory synapses in the brain are built on actin-rich dendritic protrusions called spines and, as numerous psychiatric and neurological diseases are accompanied by alterations of spine numbers or size, the elucidation of mechanisms that regulate formation and plasticity of spinous synapses is vital.
moreMar. 02, 2012
How do real neural networks, composed of numerous different types of neurons, interconnected by complex arrangements of synapses, process information? Randy M. Bruno, Ph.D., Assistant Professor at the Department of Neuroscience, Columbia University, NY, USA is pursuing this question using the rodent whisker-barrel system. Here, anatomically and functionally distinct networks - barrels and barrel columns - are clearly identifiable, and the sensory transducers that provide input are directly controllable.
moreFeb. 16, 2012
Leica Microsystems and APE, Berlin have developed a fully integrated confocal system with the capability for CARS (Coherent Anti-Stokes Raman Scattering) imaging, the Leica TCS CARS.
The microscope system is based on the Leica TCS SP5 II and benefits from imaging at video rate and a resolution of 8 x 8 Mpx for morphological studies.