Sep. 11, 2014
Fluorescent proteins have revolutionized molecular and cellular biology by offering the genetically encodable and versatile biosensors to image life processes. However, the fluorescence mechanisms of these biosensors remains elusive. Using femtosecond stimulated Raman spectroscopy, we reveal the structural dynamics basis of a new calcium ion (Ca2+) biosensor by capturing images of one of the fastest chemical reactions in proteins, namely, excited state proton transfer, starting from time zero.
moreJun. 23, 2014
Confocal Raman Microscopy is a high-resolution imaging technique that has become widely used for the characterization of materials and specimens in terms of their chemical composition. With 2D and 3D Raman images, information regarding the chemical compounds and their distribution wihtin the sample can be illustrated clearly. Newly developed software solutions for data acquisition, evaluation, and processing support the management and visualization of even large Raman data sets while providing usability for all experience levels and requirements [1,2,3].
moreApr. 24, 2014
There are two methods to determine the number of layers of nano-materials like Graphene or Molybdenum disulfide (MoS2) with Raman spectroscopy: Measuring the intralayer vibrational modes (fingerprint spectral region) and measuring the interlayer modes (very low frequencies region).
moreApr. 15, 2014
Carbon nanotubes are expected to be used in a myriad of applications ranging from military protective clothing to hydrogen storage. Due to their nanometer dimensions, however, the structure and surface chemistry of individual carbon nanotubes cannot be easily studied using conventional techniques. Norihiko Hayazawa and colleagues from the Near Field NanoPhotonics Research Team at the RIKEN Center for Advanced Photonics have now developed a high-resolution microscopy technique that can resolve individual carbon nanotubes under ambient conditions. The work has been published in Nature Communications.
moreMar. 31, 2014
Toptica´s TopMode is a high-coherence, high-power diode laser which operates as easily as a HeNe-laser.
The proprietary CoHerence-Advanced Regulation Method (CHARM) provides active stabilization of the lasers' coherence and ensures continuous single-frequency operation for excellent stability of lasing wavelength and output power. Featuring a spectral width of less than 5 MHz (a coherence length greater than 20 m), the TopMode is available at six wavelengths from 405 nm to 685 nm.
moreMar. 28, 2014
WITec and Tescan have introduced RISE Microscopy, a correlative microscopy technique which combines confocal Raman Imaging and Scanning Electron (RISE) Microscopy within one integrated microscope system.
moreMar. 27, 2014
RISE Microscopy is a novel correlative microscopy technique that combines Scanning Electron Microscopy (SEM) and confocal Raman Imaging. Through RISE Microscopy ultra-structural surface properties can be linked to molecular compound information.
moreFeb. 12, 2014
The Horiba Scientific XploRA nano integrates Scanning Probe Microscopy with Raman Spectroscopy for simultaneous and ultra-fast measurements of physical properties and chemical composition.
Optimized for highest optical throughput and stability, the XploRA nano excels at imaging. Thanks to specialized plasmonic probes now available from Horiba Scientific, it makes tip-enhanced Raman imaging easier than ever, with resolution better than 10 nanometers.
moreAug. 29, 2013
Using carbon nanotubes, a research team led by Professor Hyung Gyu Park in collaboration with Dr. Tiziana Bond has developed a sensor that greatly amplifies the sensitivity of commonly used but typically weak vibrational spectroscopic methods, such as Raman spectroscopy. This type of sensor makes it possible to detect molecules present in the tiniest of concentrations.
moreJun. 13, 2013
WITec will host the 10th Symposium on "Confocal Raman Imaging". The Raman Spectroscopy community will meet from September 30th to October 2nd, 2013 in Ulm, Germany. The symposium will cover various aspects of modern Raman microscopy and will provide deep insights into confocal Raman imaging and its applications.