SFM
Dec. 22, 2009
A prerequisite for an understanding of the mechanisms of nerve regeneration and neuronal development is the understanding of the principles of force generation in growth cones - the mechanical and chemical sensor of a neuron. In our working group we try to approach this issue from a variety of different aspects, combining experimental and theoretical studies of actin networks, membrane fluctuations and focal adhesion sites.
moreDec. 17, 2009
A fundamental step in cell migration is the advancement of the cell's leading edge. It is generally accepted that this motion is driven by actin polymerization against the plasma membrane but this has not been directly measured.
moreJan. 01, 2007
Oscillation-induced Static Deflection in SFM: L.-O. Heim and D. Johannsmann from the Max Planck Institute for Polymer research, Mainz and the Clausthal University of Technology, Clausthal-Zellerfeld, Germany, employed an atomic force microscope (AFM) in conjunction with a quartz crystal microbalance in order to investigate how a high-frequency lateral oscillation of the substrate influences the imaging process of the AFM. After characterization of the effects they demonstrated a mode of imaging based on it.
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