Jan. 17, 2015
A new Emmy Noether Junior Research Group based in LMU's Faculty of Physics has just begun its quest for new methodologies in super-resolution microscopy specifically tailored for biomedical applications.
The goal of the newly established Emmy Noether Research Group in the Faculty of Physics at LMU is to enhance the technical capabilities of fluorescence microscopy specifically in the context of its biomedical application. The research team is headed by Dr. Ralf Jungmann, who holds a dual appointment as a Research Group Leader at the Max Planck Institute of Biochemistry in Martinsried. Jungmann and his team hope to develop new DNA-based fluorescence probes that enable them to simultaneously visualize diverse cell components at the single-molecule level.
moreDec. 27, 2014
The report segments the global microscopy market by product, application, end user, and geography. The optical microscopy segment accounted for the largest share of the global microscopy market, by product. However, the electron microscopes segment is expected to grow at the highest CAGR in the forecast period. Super-resolution microscopes are the key playing field in the microscopy product market, owing to ongoing technological advancements in this segment.
moreDec. 01, 2014
STED microscopy was the first method to fundamentally break the diffraction barrier. Twenty year later, the latest generation of commercial STED microscopes further boosts the resolution by using programmable SLMs to shape and optimize the STED light pattern. This enables the highest resolutions currently possible with figures below 25 nm in 2D and below 80 x 80 x 90 nm in 3D.
moreNov. 19, 2014
After the successful FOM2014 conference held in Sydney, Australia this year, it is a pleasure to announce FOM2015, the next Focus on Microscopy conference. It will take place in Göttingen, Germany in the week before Easter from Sunday March 29 to Wednesday April 1, 2015. Focus on Microscopy 2015 is the continuation of a yearly interdisciplinary conference series running now for well over two decades. It presents the latest innovations and new trends in multi-dimensional light microscopy, super-resolution and image processing together with their application in biology, medicine and material sciences.
moreNov. 07, 2014
With the help of super-resolution microscopy, new research at University of Toronto Mississauga could help stop "superbugs" in their tracks. The Milstein Lab is taking a very close look at bacterial cells in hopes of figuring out how to stop the spread of antibiotic-resistant bacteria known as CRE or carbapenem-resistant Enterobacteriaceae. Dubbed the "nightmare bacteria," CRE infections are immune to even the strongest antibiotics and have the ability to transfer that drug resistance to other bacteria.
moreOct. 30, 2014
We review here a new generation of far-red fluorescent probes for live-cell imaging, which are based on a novel cell-permeable silicon rhodamine (SiR) dye. These probes combine a variety of desirable features, such as excellent selectivity, fluorogenicity, high brightness and low cytotoxicity, rendering them ideal probes for conventional and state-of-the-art super-resolution microscopy. Application of these new probes in combination with STED microscopy revealed for the first time the nine-fold symmetry of the centrosome and confirmed the spatial organization of actin in the axon of cultured neurons in living cells.
moreOct. 27, 2014
Microscopy Research & Techniques: Stefan Hell, 2014 Chemistry Nobel prize co-winner: View Professor Hell´s foreward and collection of research articles published in the journal - free until the end of December 2014
moreSep. 26, 2014
In the past two decades, super-resolution microscopy has been one of the fastest evolving fields through many technical improvements. However, the development of new labeling tools, probes and their biological application, is mostly lagging behind the technical capabilities. Most recently, Prof. Silvio O. Rizzoli from the Cluster of Excellence and DFG- Research Center for Nanoscale Microscopy and Molecular Physiology of the Brain (CNMPB) has developed together with his team a new technique that expands the benefit of super- resolution microscopy to study biological questions. This method contributes to understand on how cells renew, distribute and transport their molecular and subcellular components. The new technique was published the Journal of Cell Biology.
moreAug. 24, 2014
Confocal laser scanning microscopes (CLMs) are renowned for their sectioning capability. This feature is enabled by the use of pinhole, which rejects out-of-focus light. Less appreciated, on the other hand, is the gain in lateral resolution by this type of microscopes for one obvious reason.
moreAug. 11, 2014
The conference Labeling & Nanoscopy will take place from 24-26 September 2014 in Heidelberg, Germany. This conference brings together experts in fluorescence and labeling with those designing and applying new concepts of far-field optical nanoscopy.