Nov. 02, 2011

Imaging Motile Malaria Parasites

Cell motility is an essential process for most uni- and multi-cellular forms of life. The study of evolutionary ancient and thus divergent cells can yield interesting insights into our very basic understanding of molecular processes conferring cellular motility. The Plasmodium sporozoite represents a unique cell that migrates in vitro in near perfect circles due to its crescent shape. This allows the combination of high throughput imaging with reverse genetics to dissect how these cells move. more