Apr. 04, 2014
In biology, a protein's shape is key to understanding how it causes disease or toxicity. Researchers who use X-rays to take snapshots of proteins need a billion copies of the same protein stacked and packed into a neat crystal. Now, scientists using exceptionally bright and fast X-rays can take a picture that rivals conventional methods with a sheet of proteins just one protein molecule thick.
moreFeb. 09, 2014
By using a novel X-ray technique, researchers have observed a catalyst surface at work in real time and were able to resolve its atomic structure in detail. The new technique, pioneered at DESY's X-ray light source PETRA III, may pave the way for the design of better catalysts and other materials on the atomic level. It greatly speeds up the determination of atomic surface structures and enables live recordings of surface reactions like catalysis, corrosion and growth processes with a time resolution of less than a second.
moreJun. 04, 2012
In the centennial year of Max von Laue's discovery that X-ray diffraction can be used to unravel the atomic architecture of molecules, a new approach to the determination of high-resolution structures has been demonstrated. An international team of researchers has analyzed tiny protein crystals using short pulses of X-ray light from the hard X-ray free-electron laser, the US Department of Energy's 300 million dollar Linac Coherent Light Source at Stanford.
moreDec. 08, 2011
The Laboratory of Polymer Chemistry at the Université Libre de Bruxelles is focused on research into "small molecules", namely, liquid crystalline semiconductors for organic electronics application. Various organic semiconductors have been receiving a great deal of attention in "plastic" electronic devices such as organic photovoltaic cells, light-emitting diodes (OLED) and field effect transistors (OFET).
moreOct. 26, 2011
A special method of Transmission Electron Microscopy (TEM) samples preparation is described in this article. Rapidly solidified alloy have very fine structure formed by matrix and intermetallic phases. Common TEM sample of bulk material allows observe the distribution of intermetallic particles but not their detail characteristic because of their small size. To describe the intermetallic phases is necessary to extract them from matrix. It is possible to do that by selective matrix dissolution in the solution of tartaric acid and iodine in methanol.
moreSep. 19, 2011
Martensitic VM12 steel was recently developed for advanced coal-fired power stations. Its creep resistance is dependent on a stability of microstructure. Destabilization of microstructure is caused by recovery and softening processes of a tempered martensite and depends on changes of a dislocation substructure and morphology of secondary particles during creep. Quantitative TEM analyses of VM12 steel were undertaken to determine the microstructure parameters after creep at 625°C up to 30.000h.
moreNov. 02, 2010
H. Jiang and co-workers bridged the visualization gap between 3D optical microscopy and 3D electron microscopy by demonstrating the quantitative 3D imaging of a whole unstained cell by X-ray diffraction microscopy at a resolution of 50-60 nm. Subcellular structures and organelles could be identified and the resolution can be even further improved by cryotechnology.
moreNov. 05, 2009
X-Ray Diffraction (XRD) is a high-tech, non-destructive technique for analyzing a wide range of materials. Throughout industry and research institutions, XRD has become an indispensable method for materials investigation, characterization and quality control. Example areas of application include over others, qualitative and quantitative phase analysis, crystallography, structure and relaxation determination, micro-diffraction, nano-materials, lab- and process automation, and high-throughput polymorph screening.
moreNov. 01, 2007
Cryo Electron Tomography: Unique Capability for Structural Biology InvestigationsCryo electron tomography's (CET) ability to visualize three dimensional biological structures - ranging in size from molecular to cellular - fills a critical gap between techniques with atomic resolution, such as x-ray diffraction (XRD) and nuclear magnetic resonance (NMR), and conventional light microscopy. However, it is CET's ability to investigate biological structures in their unperturbed, native context that makes it an indispensable tool in the currently exploding field of structural biology.