Dec. 15, 2010A better understanding of the micro- and nanostructures of cellulose fiber composition before and after various chemical treatments together with the distribution of bleaching additives to the final paper composition is essential for further improvements of paper properties. Confocal Raman imaging is a valuable tool for such studies, as it not only reveals optical information but also information regarding the 3D distribution of the chemical compounds in the sub-micrometer range [1-3].
moreNov. 16, 2010Scientists long to understand the architecture of life. They want to learn how biological structures are arranged in respect to one another. Do they co-localize within or are they excluded from the same superstructure? Does localization follow a special pattern and how does the overall arrangement reflect the biological function? Multicolor superresolution imaging allows these fundamental questions to be addressed by far-field fluorescence microscopy in unprecedented detail.
moreSep. 27, 2010Bridging the Micro and Nano World: One specimen, two microscope technologies, a new depth of information - this simple formula impressively summarizes the idea behind correlative light and electron microscopy. Particularly in the life sciences, the relationship between structure and function is increasingly becoming a focal point of interest.
moreSep. 15, 2010Nanoindentation is an important tool in the broad field of materials testing. It is derived from the classical hardness test, but is carried out on a much smaller scale.
moreJul. 13, 2010The macroscopic properties of technical materials are often determined by their elemental composition. Because most technical materials are inhomogeneous analytical methods are required that allow elemental analysis of these inhomogeneities - not only as a point by point measurement but also as a complete 2D-distribution. Micro X-ray fluorescence (µ XRF) has recently been established for this purpose.
moreJun. 15, 2010Olympus has recently launched a range of versatile fluorescence research microscope systems. The xcellence line covers advanced live cell techniques, including real-time, high-speed imaging, TIRFM & HILO (cell^tirf), and photo control such as FRAP, FLIP & photo activation (cell^frap). With a series of new features, this portfolio enables users to continue advancing their microscopy research.
moreApr. 14, 2010Live cell imaging is one of the most rapidly evolving areas of life science research. The more researchers see, the more they want to see and this is driving innovation in imaging technologies to see deeper, clearer and faster. While light is the fundamental enabling factor in optical microscopy, light can also create significant barriers when trying to image biological samples. Visible light, for example, cannot pass easily through living tissue and is scattered, preventing it from reaching areas of interest in thicker specimens.
moreFeb. 15, 2010For the three „global killer diseases", HIV/ AIDS, TB and Malaria, fast and reliable diagnosis is crucial for modern laboratory practices. In resource-limited settings, for example, TB is diagnosed by using sputum smears with microscopy for which fluorescence based microscopic techniques have shown to be much more sensitive than transmitted light microscopy, where M. tuberculosis bacilli in a significant number of cases are not seen.
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