Imaging & Microscopy en Olympus EP50 Camera Engages Classrooms The WLAN-capable Olympus EP50 camera allows every microscope in a classroom to become a wireless imaging system, while also facilitating full stand-alone applications. The 5-megapixel color camera combines a full HD live image with fast, real-time sharing via smartphones and tablets – without the need for a PC. Tue, 23 Jul 2019 15:18:00 +0000 Standard Light Microscopes Get an Upgrade to See Inside Cells Researchers can now see the molecules inside cells using standard light microscopes. Traditionally, light microscopes could only reveal the shape of large structures inside cells, and not the distribution of molecules. The microscope upgrade is an attachable unit that researchers call the “molecular-contrast unit,” which contains an infrared laser light source. No specialized preparation of the cells, for example labeling with fluorescent dyes, is required. Tue, 23 Jul 2019 08:50:00 +0000 Seeing is Believing - Imaging the Molecular Processes of Life The processes of life are naturally dynamic in space and time from the atomic to the organismal level. The rapid development of imaging methods across this full scale of biological organisation is revolutionising our ability to visualise the inner workings of proteins, protein complexes, organelles, cells, tissues, organs and whole organisms. Being able to see biological processes unfold in real time allows us to understand the mechanism of life as well as disease. Mon, 22 Jul 2019 12:49:00 +0000 Park Systems AFM Scholarship Awards Park AFM Scholarship Awards are open to undergraduate or postdoctoral students. Through this program, Park Systems has offered assistance to many researchers around the world who qualify as Park AFM Scholars by matching them with one of thousands of nanoscience shared user facilities to perform their research using Park AFMs. Mon, 22 Jul 2019 06:53:00 +0000 Ultrasound-assisted Optical Imaging Carnegie Mellon University's Assistant Professor of Electrical and Computer Engineering (ECE) Maysam Chamanzar and ECE Ph.D. student Matteo Giuseppe Scopelliti published research that introduces a novel technique which uses ultrasound to noninvasively take optical images through a turbid medium such as biological tissue to image body's organs. Wed, 17 Jul 2019 12:22:00 +0000 Discover Hidden Details with the Next-generation Super-resolution Microscope The extensive imaging capabilities offered by DeltaVision OMX Flex make it an excellent choice to support a wide range of research projects. Confocal and super-resolution functionality is combined into one instrument giving you the flexibility to image any biology at any level of resolution, contrast, depth, or speed. See beyond the diffraction limit using the microscopy application of your choice. Tue, 16 Jul 2019 07:14:00 +0000 Compact Ultrafast Laser Lowers Costs for Microscopy and Other Applications Coherent has introduced the Axon family, a completely new suite of compact femtosecond lasers, designed from inception to deliver lower cost, reduced complexity, and smaller footprint. Tue, 16 Jul 2019 06:25:00 +0000 Imaging Molecules in Different Charge States Energy conversion and energy transport in living systems relies on charging and discharging molecules. Most important in this aspect is the family of porphyrins, comprising chlorophyll and hemoglobin. The charge transitions of these molecules are essential for life. Charge transitions of molecules also play a crucial rule in organic electronic and organic photovoltaic devices. Mon, 15 Jul 2019 16:33:00 +0000 Scanning Quantum Dot Microscopy Control Engineers of the Otto von Guericke University Magdeburg, in collaboration with colleagues from the Jülich Research Center, have developed a method for measuring the electrical potentials of molecules and molecular surfaces with previously unattainable precision and speed. Fri, 12 Jul 2019 07:12:00 +0000 Secondary Electron Energy Matters Secondary Electron (SE) Imaging in Scanning Electron Microscopes is fundamental to Materials Science including polymers - yet it lacks nanoscale chemical information, unless samples are stained. Change comes when sets of images using SEs with defined energy ranges (Hyperspectral SE Imaging) can be collected to build SE spectra that allow identification of particular energy ranges in terms of chemistry/polymer morphology either by modelling or comparison with other spectroscopy techniques. Introduction Fri, 12 Jul 2019 05:08:00 +0000 New Imaging Method Aids in Water Decontamination A breakthrough imaging technique developed by Cornell researchers shows promise in decontaminating water by yielding surprising and important information about catalyst particles that can’t be obtained any other way. Peng Chen, the Peter J.W. Debye Professor of Chemistry, has developed a method that can image nonfluorescent catalytic reactions – reactions that don’t emit light – on nanoscale particles. Thu, 11 Jul 2019 11:59:00 +0000 It’s not an Antibody, it’s a Frankenbody Antibodies are the biomolecules our immune systems deploy to find, tag and destroy invading pathogens. They work by binding to specific targets, called epitopes, on the surfaces of antigens – like locks to keys. Wed, 10 Jul 2019 07:14:00 +0000 New Olympus Stream Software - Inspection Without Limitation New Olympus Stream 2.4 image analysis software enables users of any experience level to conduct complex image analysis tasks, from image acquisition to reporting, under any imaging condition. With a host of new features, Olympus Stream offers fully tailored solutions for all manufacturing, QC and research applications. Mon, 08 Jul 2019 18:04:00 +0000 New Technique Allows Real-time Microscopy at High Heat and Loading Researchers have demonstrated a technique that allows them to track microscopic changes in metals or other materials in real time even when the materials are exposed to extreme heat and loads for an extended period of time - a phenomenon known as "creep." The technique will expedite efforts to develop and characterize materials for use in extreme environments, such as nuclear reactors. Mon, 08 Jul 2019 16:34:00 +0000 AI Meets Live Cell Imaging The Olympus scanR 3.1 high-content screening station uses the power of AI to carry out groundbreaking analyses of live cells – analyses that until recently seemed impossible. Its software’s accuracy, robustness and ease of use improve both data quality and cell viability, enabling fast analyses and confidence in results. Mon, 08 Jul 2019 15:20:00 +0000 Camera Brings Unseen World to Light When the first full-length movie made with the advanced, three-color process of Technicolor premiered in 1935, The New York Times declared "it produced in the spectator all the excitement of standing upon a peak ... and glimpsing a strange, beautiful and unexpected new world." Technicolor forever changed how cameras - and people - saw and experienced the world around them. Today, there is a new precipice - this one, offering views of a polarized world. Fri, 05 Jul 2019 10:04:00 +0000 Webinar: Single Cell Injection, Deposition and Aspiration One of the challenges in single cell biology is to address and manipulate single cells locally while being able to monitor their reaction after the manipulation. Tue, 02 Jul 2019 07:10:00 +0000 Determing the Elasticitiy of Graphene Atomic force microscopy based nanoindentation technique provides a powerful approach to determine the elasticity of graphene. From the recorded force-displacement response, free standing graphene shows stiffness of 1TPa, which is the strongest material ever measured. In our work,the elasticity of graphene on substrate is investigated and the result shows system stiffness of 100 GPa, which indicates the role of graphene as a ultrathin surface reinforcing layer.   Introduction Mon, 01 Jul 2019 05:50:00 +0000 “DNA Microscopy” Rather than relying on optics, a new microscopy system offers a chemically encoded way to map biomolecules’ relative positions. Microscopy just got reinvented – again. Traditionally, scientists have used light, x-rays, and electrons to peer inside tissues and cells. Today, scientists can trace thread-like fibers of nerves throughout the brain and even watch living mouse embryos conjure the beating cells of a rudimentary heart. But there’s one thing these microscopes can’t see: what’s happening in cells at the genomic level. Tue, 25 Jun 2019 10:26:00 +0000 Cobolt Skyra: The New Multi-Line Laser Cobolt AB, Swedish manufacturer of high performance lasers, proudly introduces the Cobolt Skyra, a revolutionary multi-line laser platform. Offering up to 4 laser lines in a box that can fit into the palm of your hand (70 x 134 x 38 mm) and requiring no external electronics, the Cobolt Skyra will enable the next generation of compact and easy-to-use analytical instrumentation for the life science market. Tue, 25 Jun 2019 05:13:00 +0000 Microscience Microscopy Congress Coming Soon The Microscience Microscopy Congress 2019 will include 36 conference sessions, an exhibition with more than 90 companies represented. In addition, it includes a range of pre-congress and satellite meetings, corporate workshops, teaching and learning facilities, and a well-established and fun social program. The conference will begin on Monday 1 July with a number of Pre-Congress Workshops addressing and demonstrating some of the latest techniques and software. Mon, 24 Jun 2019 11:44:00 +0000 A New Force for Optical Tweezers Awakens When studying biological cells using optical tweezers, one main issue is the damage caused to the cell by the tool. Giovanni Volpe, University of Gothenburg, has discovered a new type of force that will greatly reduce the amount of light used by optical tweezers – and improve the study of all kinds of cells and particles. Fri, 21 Jun 2019 13:17:00 +0000 Find, Classify and Identify Microparticles with Raman Imaging High-resolution measurements of particles are of great interest in many fields of application. Combining confocal Raman microscopy with particle analysis tools makes it possible to find, classify and identify particles almost entirely automatically. Fri, 21 Jun 2019 05:27:00 +0000 Read & Win: Electron Beam-Specimen Interactions and Simulation Introduces electron beam scattering in the context of simulation methods, since the practicing microscopist is usually concerned with the latter. Despite the availability of user-friendly software, some understanding of the underlying physics is essential, both to ‘optimise’ the simulation and recognise its limitations and to correctly interpret and/or generalise the results. The book highlights applications with examples made possible by the significant advances in instrumentation, e.g. Fri, 21 Jun 2019 05:02:00 +0000 Stretching DNA Using Cryo-Force Spectroscopy Mechanical properties of micrometer long DNA have mainly been probed at room temperature with a force resolution limited by thermal fluctuations. Cryo-force spectroscopy combined with computer simulations now enables to quantify adhesion and intra-molecular mechanics at the sub-nanometer level by stretching up to several nano-newton tensile loads spray-deposited single-strand DNA oligomers on surfaces in ultrahigh vacuum. Thu, 20 Jun 2019 05:55:00 +0000