Imaging & Microscopy en Oxford Instruments Announces All-New Ergo Software for Asylum Research Atomic Force Microscopes Oxford Instruments today announced the launch of the new Ergo software platform for their Asylum Research atomic force microscopes (AFMs). Based on the acclaimed AZtec software interface for Oxford Instruments electron microscope analyzers, Ergo improves the productivity of both infrequent and expert AFM users. A streamlined workflow guides users quickly from setup to data acquisition. Intelligent algorithms automatically calculate the optimal imaging settings to achieve consistent, high-quality images. Mon, 09 Sep 2019 15:35:00 +0000 “Resonance” Raman Spectroscopy with 1-nm Resolution Tip-enhanced Raman spectroscopy resolved “resonance” Raman scattering with 1-nm resolution in ultrathin zinc oxide films epitaxially grown on a single-crystal silver surface. Tip-enhanced “resonance” Raman scattering can be used to investigate a specific chemical structure at nanoscale and even at the single-molecule level and also provides a new approach for the atomic-scale optical characterization of local electronic states. Thu, 05 Sep 2019 07:24:00 +0000 Graphene Layer Enables Advance in Super-Resolution Microscopy Researchers at the University of Göttingen have developed a new method that takes advantage of the unusual properties of graphene to electromagnetically interact with fluorescing (light-emitting) molecules. This method allows scientists to optically measure extremely small distances, in the order of 1 ångström (one ten-billionth of a meter) with high accuracy and reproducibility for the first time. Thu, 05 Sep 2019 05:48:00 +0000 Revealing Details in DNA Origami Nanostructures Scientists at the U.S. Department of Energy’s Ames Laboratory are now able to see greater details of DNA origami nanostructures, which will lead to a greater understanding and control of their assembly for future applications. Wed, 04 Sep 2019 07:44:00 +0000 Tescan Amber X: A Unique Combination of Plasma FIB and Field-Free UHR FE-SEM As the first SEM manufacturer to commercialize integrated xenon plasma FIB with the SEM, Tescan proudly announces Tescan Amber X. Tescan Amber X is a new FIB-SEM solution that combines high throughput plasma-assisted ion milling with improved ultra-high resolution (UHR) field-free SEM optics, a combination ideally suited for materials characterization over a significantly wider sample range. Mon, 02 Sep 2019 15:45:00 +0000 Cryo-Electron Microscopy The enzyme transhydrogenase plays a central role in regulating metabolic processes in animals and humans alike. Malfunction can lead to serious disorders. For the first time, structural biologists at the Institute of Science and Technology Austria (IST Austria) have now visualized and analyzed the enzyme’s atomic structure with the support of the institute’s newly installed high-end cryo-electron microscope. Fri, 30 Aug 2019 14:30:00 +0000 Chemistry in Motion For the first time, researchers have managed to view previously inaccessible details of certain chemical processes. They have shown there are significant discrete stages to these processes which build on our knowledge of chemical synthesis. These details could aid in the development of methods to synthesize chemicals with greater control and precision than ever before. Methods such as these could be useful in materials science and in drug development. Mon, 26 Aug 2019 11:08:00 +0000 Mapping Nucleation Kinetics with Nanometer Resolution Nucleation is the formation of a new condensed phase from a fluid phase via self-assembly. This process is critical to many natural systems and technical applications including the manufacturing of pharmaceuticals and advanced materials, the formation of clouds, mineral formation in the Earth’s crust, and the stability of proteins. While scientists have studied nucleation for over a century, it remains an elusive process because it occurs sporadically in time. Moreover, a nucleus can be less than a nanometer (10-9 m) in size. Sat, 24 Aug 2019 09:05:00 +0000 Webinar: Multiscale Microstructural Analysis of Rocks Rocks are heterogeneous at all scales in composition, microstructure and petrophysical properties. Pore geometries and associated mineral phases and fluids are important properties in reservoir rocks and seals. Thu, 22 Aug 2019 06:28:00 +0000 Driving the Innovation Pipeline in Biological Imaging When sparks fly to innovate new technologies for imaging life at the microscopic scale, often diverse researchers are nudging each other with a kind of collegial one-upmanship. "Look at the resolution we obtain with this microscope I've designed," the physicist says. "Great," the biologist replies, "but my research organism moves fast. Can you boost the system's speed?" "You'll have terabytes of raw data coming off that microscope system," says the computational scientist. Thu, 22 Aug 2019 04:43:00 +0000 Super-resolution Method Could Bring Nanoscale Microscopy to Every Lab The ability to observe how life works at a nanoscale level is a grand challenge of our time. Standard optical microscopes can image cells and bacteria but not their nanoscale features which are blurred by a physical effect called diffraction. Optical microscopes have evolved over the last two decades to overcome this diffraction limit; however, these so-called super-resolution techniques typically require expensive and elaborated instrumentation or imaging procedures. Mon, 19 Aug 2019 12:49:00 +0000 Volumetric Fluorescence Imaging Fluorescence microcopy is one of the most widely used tools for investigating the dynamics of biological systems. Such dynamics, for example the propagation of neural signals in the brain, often plays out in all three spatial dimensions. This is challenging for microscopy which typically only monitors a single two-dimensional focal plane at a time. To address this problem, we developed a fluorescence tomography approach to record volume information in a single frame scan from sparsely labeled samples. Mon, 19 Aug 2019 11:39:00 +0000 Dynamic Secondary Ion Mass Spectrometry Surface analysis is the cornerstone of a wide range of scientific disciplines, from materials science and electronics to geology and biology. Still the most sensitive surface analysis technique available, secondary ion mass spectrometry (SIMS) provides localized elemental, isotopic and molecular characterization of the sample surface. Fri, 16 Aug 2019 12:06:00 +0000 Job Offer: Bioimaging Network Project Officer UK This position will fill a critical role in the delivering the aims of the BioImagingUK Network Wed, 14 Aug 2019 06:05:00 +0000 Focused Ion Beam-Scanning Electron Microscopy With any kind of work, it helps to be able to see what you’re doing, but that can be a challenge when working at microsc Tue, 13 Aug 2019 07:07:00 +0000 The Art of Science: Olympus Launches the First Global Image of the Year Award Inspired by the beauty and breadth of images submitted for the 2018 Image of the Year Life Science Light Microscopy Award held in Europe, Olympus has launched its first Global Image of the Year Life Science Light Microscopy Award. Wed, 07 Aug 2019 15:37:00 +0000 Non-invasive Imaging Method Spots Cancer at the Molecular Level Researchers for the first time have combined a powerful microscopy technique with automated image analysis algorithms to distinguish between healthy and metastatic cancerous tissue without relying on invasive biopsies or the use of a contrast dye. This new approach could one day help doctors detect cancer metastasis that is otherwise difficult to see via standard imaging technologies during operations. Wed, 07 Aug 2019 06:55:00 +0000 Advanced BSE Detection Capabilities of the Tescan UHR-SEM The BSE (Back Scattered Electron) image contrast differs depending on both the take-off angle and energy of backscattered electrons. This contrast change needs to be visualized as some information may remain hidden when using more conventional BSE detection systems. The new Tescan Clara ultrahigh-resolution scanning electron microscope (UHR-SEM), based on Tescan's BrightBeamTM technology, enables variable, filtered BSE detection. Tue, 06 Aug 2019 16:19:00 +0000 Google Maps for Tissues Modern light microscopic techniques provide extremely detailed insights into organs, but the terabytes of data they produce are usually nearly impossible to process. New software, developed by a team led by MDC scientist Dr. Stephan Preibisch and now presented in Nature Methods, is helping researchers make sense of these reams of data. Mon, 05 Aug 2019 15:45:00 +0000 New Laser Tools Benefit Confocal and Multiphoton Microscopy New wavelengths, flexible multi-laser systems and higher power are key trends in CW lasers for confocal instruments, while new compact economical femtosecond lasers will benefit both OEMs and end users in multiphoton imaging. Mon, 29 Jul 2019 07:17:00 +0000 Toptica Among “Bayerns Best 50“ The Award “Bayerns best 50” was presented on July 22nd, by Bavaria's Minister of Economic Affairs Hubert Aiwanger at a ceremony in Schleissheim Castle. Toptica Photonics is now also officially one of the 50 best companies in Bavaria. The Bavarian State Ministry of Economic Affairs once again honored Bavarian companies that are particularly innovative, creative, and flexible – and enjoyed a significant above-average growth. Fri, 26 Jul 2019 14:13:00 +0000 Terahertz Imaging Technique Reveals Subsurface Insect Damage in Wood Insect infestation is becoming an increasingly costly problem to the forestry industry, especially in areas experiencing increased droughts and hot spells related to climate change. A new terahertz imaging technique could help slow the spread of these infestations by detecting insect damage inside wood before it becomes visible on the outside. Fri, 26 Jul 2019 09:05:00 +0000 Closing the Terahertz Gap: Tiny Laser is an Important Step Toward New Sensors In a major step toward developing portable scanners that can rapidly measure molecules in pharmaceuticals or classify tissue in patients' skin, researchers have created an imaging system that uses lasers small and efficient enough to fit on a microchip. Thu, 25 Jul 2019 07:55:00 +0000 Compact Ultrafast Laser Lowers Costs for Microscopy and Other Applications Coherent has introduced the Axon family, a completely new suite of compact femtosecond lasers, designed from inception to deliver lower cost, reduced complexity, and smaller footprint. Thu, 25 Jul 2019 06:25:00 +0000 Imaging the Chemical Structure of Individual Molecules, Atom by Atom Using atomic force microscopy images, scientists at Brookhaven Lab's Center for Functional Nanomaterials developed a guide for discriminating atoms other than hydrogen and carbon in aromatic molecules—ring-shaped molecules with special bonding properties—to help identify contaminants found in petroleum. Tue, 23 Jul 2019 17:45:00 +0000