Imaging & Microscopy en Single Molecule Imaging To understand the mechanisms by which molecules act in cells, or the effects of drugs on them, it would be ideal to be able to track individual molecules, including where in the cell they are located and what modifications they undergo when conditions in the cell change. However, this has proven difficult with existing technologies, particularly given the amount of time required to perform such monitoring. Thu, 18 Oct 2018 06:21:00 +0000 NX-Wafer - Your Solution for Semiconductor Wafer Production Park NX-Wafer is a revolutionary AFM solution designed for bare wafer manufacturing that fully automates the automatic defect review process and increases production throughput by an astounding 1,000%. Wed, 17 Oct 2018 15:12:00 +0000 Light Switch: A Custom Terahertz Pulse Cycle for Scanning Tunneling Microscopy Researchers from Japan have taken a step toward faster and more advanced electronics by developing a way to better measure and manipulate conductive materials through scanning tunneling microscopy. Wed, 17 Oct 2018 09:04:00 +0000 Miltenyi Biotec Acquires Microscopy Specialist LaVision BioTec Miltenyi Biotec GmbH, a global provider of products and services for advancing biomedical research and cellular therapy, announced that it has acquired the high-end microscopy specialist LaVision BioTec GmbH. Tue, 16 Oct 2018 11:47:00 +0000 Ultrafast Real-Time Imaging What happens when a new technology is so precise that it operates on a scale beyond our characterization capabilities? For example, the lasers used at INRS produce ultrashort pulses in the femtosecond range (10–15 s) that are far too short to visualize. Although some measurements are possible, nothing beats a clear image, says INRS professor and ultrafast imaging specialist Jinyang Liang. Mon, 15 Oct 2018 06:11:00 +0000 Cobolt 06-01 Diode Lasers: Long Warranty, No Clean-Up Filters Needed Cobolt AB, a part of Hübner Photonics, announces longer warranty for lasers in the Cobolt 06-01 Series. All lasers within this Series now come with 24 mths, unlimited hours warranty and in addition clean-up filters are now standard. Fri, 12 Oct 2018 05:51:00 +0000 Correlative Microscopy: Combining X-Ray and STED Microscope to See Molecular Details A research team from the University of Göttingen has commissioned a worldwide unique microscope combination at DESY's X-ray source PETRA III to gain novel insights into biological cells. The team led by Tim Salditt and Sarah Köster describes the combined X-ray and optical fluorescence microscope in the journal Nature Communications. Thu, 11 Oct 2018 10:51:00 +0000 Scanning Transmission Electron Microscopy A novel technique that nudges single atoms to switch places within an atomically thin material could bring scientists another step closer to realizing theoretical physicist Richard Feynman’s vision of building tiny machines from the atom up. Wed, 10 Oct 2018 05:52:00 +0000 Single‐Molecule FRET Researchers have used a special fluorescence-based imaging technique to track the shape changes that occur when pore proteins in the cell membrane export molecules into the extracellular medium. Mon, 08 Oct 2018 11:29:00 +0000 Webcast: Ultra-Thin “Metalens” Technology Light of different colors travels at different speeds in different materials and structures. This is why we see white light split into its constituent colors after refracting through a prism, a phenomenon called dispersion. An ordinary lens cannot focus light of different colors to a single spot due to dispersion. This means different colors are never in focus at the same time, and so an image formed by such a simple lens is inevitably blurred. Fri, 05 Oct 2018 11:30:00 +0000 15th Confocal Raman Imaging Symposium The Confocal Raman Imaging Symposium, which took place for the 15th time in Ulm, was like a big family reunion with both familiar and new faces. The Ulm-based microscope manufacturer WITec invited researchers, engineers and scientists to discuss the latest developments in confocal Raman microscopy from September 24th-26th, 2018. Fri, 05 Oct 2018 08:08:00 +0000 Toptica Expands Management Team From Oct 1st 2018, Dr. Thomas Renner, VP Sales & Marketing since 2005, will join the Vorstand of Toptica Photonics AG, which expands from 2 to 3 members. Next to the company founders Dr. Wilhelm Kaenders (Technology) and Dr. Thomas Weber (Operations & Finance) Dr. Renner will become responsible for sales, marketing and product management, and will focus on the expansion of the global activities of the group. Tue, 02 Oct 2018 16:52:00 +0000 3D Open-Loop Electric Potential Microscopy Charges and their transport are integral to the function of electronic devices, batteries, and biological systems. The charges that accumulate at the interface between a solid electrode and an electrolytic solution containing ions that carry charges, can affect the electrode-electrolyte interaction as well as processes such as corrosion and molecular adhesion. Tue, 02 Oct 2018 13:06:00 +0000 Nobel Prize in Physics 2018 The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Physics 2018 with one half to Arthur Ashkin, Bell Laboratories, Holmdel, USA and the other half jointly to Gérard Mourou, École Polytechnique, Palaiseau, France and University of Michigan, Ann Arbor, USA and Donna Strickland, University of Waterloo, Canada. The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Physics 2018 “for groundbreaking inventions in the field of laser physics” Tue, 02 Oct 2018 12:37:00 +0000 Phonon Microscopy A University of Nottingham academic has won a prestigious five-year fellowship to explore the use of harmless sound waves to view deep inside living cells to aid early diagnose in diseases such as cancer. Mon, 01 Oct 2018 11:12:00 +0000 Nanomechanical Scanning Absorption Microscopy A new, extremely promising microscopy technique called "Nanomechanical scanning absorption microscopy" has been developed at Technical University Vienna (TU Wien), in which sound is measured instead of light. Thu, 27 Sep 2018 08:38:00 +0000 Holotomographic Microscopy: Label-Free 3D Analysis of Organelles Mitochondria are one of the most important cell organelles. They are organized in extremely dynamic networks and, in addition to supplying the cell with energy, they have an important role in apoptosis, metabolism, and degenerative diseases. Until now it was believed that, unless specifically stained, they were not visible in microscopy. Furthermore, when fluorescent dyes are applied they are inherently phototoxic. This strongly limits acquisition frequency and length, in order to avoid perturbations to the cell and its organelles. Thu, 27 Sep 2018 07:51:00 +0000 Finally… a True Arc Lamp Replacement. Make the Switch to LED. X-Cite Xylis is a true arc lamp replacement for routine and advanced fluorescence imaging. With coverage from DAPI to Cy7, X-Cite Xylis has the broadest spectrum available in a white light LED and rivals arc lamps for brightness – making it ideal for both compound and stereomicroscopes. Wed, 26 Sep 2018 15:42:00 +0000 Nanoparticles Research Accelerated by Digital Solutions Platform Engineered nanoparticles have a wide range of industrial applications including catalyst research, electronics, inks and pigments, coatings, cosmetics, filtration, energy materials, pharmaceuticals and biomedical applications. With nanotechnology applications likely to develop rapidly in these and other industries, advancing nanoparticles research will play an important role in improving the quality of life [1]. Tue, 25 Sep 2018 08:12:00 +0000 Cryo-EM Reveals TRPM2 Structure A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and bipolar disorder. Tue, 25 Sep 2018 07:59:00 +0000 Read & Win: Fluorescence Microscopy - From Principles to Biological Applications Fluorescence Microscopy has become a very powerful tool that allows to specifically visualize structure or proteins in cells. During the last 20 years, many novel techniques have emerged to enhance spatial and or temporal resolution of live fluorescence probes. These techniques now allow for the detection of single molecules and a spatial resolution which is below the theoretical resolution limit for traditional light microscopy, approaching the resolution of electron microscopy. Tue, 25 Sep 2018 07:42:00 +0000 NanoScientific Forum Europe (NSFE) on AFM/SPM at TU Freiberg, Germany The NanoScientific Forum Europe (NSFE 2018), hosted at TU Bergakademie Freiberg and sponsored by Park Systems & NanoScientific Journal, is an exciting new opportunity for scientists to present their latest AFM/SPM research projects to leading researchers and peers from both academia and industry around Europe. CANNOT JOIN THIS TIME? Join our Live Stream on the 1st conference day: Tue, 25 Sep 2018 04:19:00 +0000 Research Devises Protocol for Measuring Distances within Biomolecules Architects cannot build a house without the proper dimensions of the foundation. Likewise, scientists cannot develop targeted drug therapies without first measuring the surfaces of biomolecules such as proteins, RNA or DNA. The best practice for gathering these measurements is hotly contested in the fields of biophysics and structural biology because scientists prefer different, personalized methods that often yield a variety of results for one given biomolecule. Tue, 18 Sep 2018 08:35:00 +0000 Cryo-EM Provides Detailed View of AAV2 The imaging method called cryo-electron microscopy (cryo-EM) allows researchers to visualize the shapes of biological molecules with an unprecedented level of detail. Tue, 18 Sep 2018 08:25:00 +0000 Raman Award for the Best Junior Researcher Microscopes let us peer into cells and the biochemical processes inside them. Processes taking place on much smaller scales, e.g. within single molecules, are the research focus of Dr. Marie Richard-Lacroix. The scientist from the Leibniz Insitute of Photonic Technology Jena (Leibniz-IPHT) and the Friedrich-Schiller University Jena examines molecules on the nanometre scale using tip-enhances Raman spectroscopy. Tue, 18 Sep 2018 07:56:00 +0000