Imaging & Microscopy en New Quantum Dot Microscope Shows Electric Potentials of Individual Atoms A team of researchers from Jülich in cooperation with the University of Magdeburg has developed a new method to measure the electric potentials of a sample at atomic accuracy. Using conventional methods, it was virtually impossible until now to quantitatively record the electric potentials that occur in the immediate vicinity of individual molecules or atoms. Fri, 14 Jun 2019 08:00:00 +0000 Discover Hidden Details with the Next-generation Super-resolution Microscope The extensive imaging capabilities offered by DeltaVision OMX Flex make it an excellent choice to support a wide range of research projects. Confocal and super-resolution functionality is combined into one instrument giving you the flexibility to image any biology at any level of resolution, contrast, depth, or speed. See beyond the diffraction limit using the microscopy application of your choice. Thu, 13 Jun 2019 07:14:00 +0000 Park Systems Europe announces: 33 Years of AFM – 33% OFF on your NEXT AFM Park Systems Europe, as a leading nanoscientific company devoted to innovative science and nanotechnology, is proud to contribute to the research growth in Europe, and dedicates a remarkable discount to all academic research facilities in Europe for new atomic force microscopy (AFM) equipment! Exactly 33 years ago Gerd Binnig, Calvin Quate and Christoph Gerber published the first paper on Atomic Force Microscopy, ever in history! Wed, 12 Jun 2019 12:20:00 +0000 Direct Atom-resolved Imaging of Magnetic Materials In conventional electron microscopes, performing atomic-resolution observations of magnetic materials is particularly difficult because high magnetic fields are inevitably exerted on samples inside the magnetic objective lens. A newly developed magnetic objective-lens system provides a magnetic-field-free environment at the sample position. This enables direct, atom-resolved imaging of magnetic materials such as silicon steels. This novel electron microscope is expected to be extensively used for the research and development of advanced magnetic materials. Tue, 11 Jun 2019 16:17:00 +0000 Manipulating Nanoscale Light in Nanocavity of Scanning Tunneling Microscope Junction Manipulating nanoscale light in scanning tunneling microscope junctions is attained by nanofabrication of gold tips using a focused ion beam technique. Researchers at Fritz-Haber Institute, Berlin, Germany, demonstrated that a spectrum of “nanolight” in a nanoscale plasmonic junction can be modulated with plasmonic Fabry–Pérot tips. Mon, 10 Jun 2019 19:36:00 +0000 Microscope-on-a-Chip Focuses on Super-Resolution Viewing An EU-funded project is developing a super-resolution microscope small enough to fit on to a computer chip that can be used to see changes in living cells in real time. Potential applications include a wide range of science and research fields, as well as consumer goods, with the innovation potential to strengthen European industry. Wed, 29 May 2019 07:42:00 +0000 Precision Positioning of Samples and Objectives Whether classical stereo microscopy, fluorescent, widefield or laser scanning microscopy, whether SEM, FIB-SEM, TEM, AFM or correlative microscopy - positioning samples and objectives with subnanometer precision is decisive for the quality of your results with all of these techniques. This fully clickable, new “Nanopositioning for Microscopy” brochure provides a comprehensive overview of objective scanners and sample stages with up to six degrees of motion freedom – illustrated by a variety of today’s microscopy techniques. Mon, 27 May 2019 10:37:00 +0000 Reveal More in Super-Resolution Microscopy Key Features: Designed for convenience, efficiency, sensitivity and results. EDGE enhanced confocal imaging improves resolution and contrast Easily switch between multiple imaging modes with one click Improved system sensitivity uses less light, reduces photobleaching The new GE Healthcare DeltaVision OMX Flex microscope with EDGE confocal imaging: the next generation super-resolution microscope. Thu, 23 May 2019 09:13:00 +0000 Imaging of Golgi Apparatus in Yeast The transport of cargo in a tiny cellular structure, or organelle, called the Golgi apparatus has been visualized in living yeast cells for the first time by RIKEN researchers. This advance should help researchers gain a better understanding of how diseases arise when this transport goes awry. Tue, 21 May 2019 16:34:00 +0000 Manipulating Atoms One at a Time with an Electron Beam The ultimate degree of control for engineering would be the ability to create and manipulate materials at the most basic level, fabricating devices atom by atom with precise control. Now, scientists at MIT, the University of Vienna, and several other institutions have taken a step in that direction, developing a method that can reposition atoms with a highly focused electron beam and control their exact location and bonding orientation. Tue, 21 May 2019 15:20:00 +0000 New Chief Marketing Officer at PicoQuant In September 2018, Frederik Siegmann joined PicoQuant as chief marketing officer to pursue a holistic approach including product management, marketing communication, and brand management. Fri, 17 May 2019 08:11:00 +0000 Technology Advances Benefit Diverse Applications, Including the THz Domain The use of Raman spectroscopy as an essential tool in chemical analysis has grown dramatically over the past few decades, primarily due to technology advances in the lasers, optical filters, and spectrometer components that comprise these instruments. We survey a few of these key developments and their impact on applications, including portable/field use and real-time measurement of crystallinity and molecular structure using THz-Raman. The Raman Advantage Thu, 16 May 2019 05:22:00 +0000 Enhanced Surface Potential Detection using Frequency Modulation SKPM Scanning Kelvin Probe microscopy (SKPM) allows measuring work function and electrical potential distribution of various materials, to provide a better understanding of nanostructures and CMOS semiconductor devices to improve their performance.[1-2] SKPM has also been used to determine quantitative information such as the charge distribution in polymer materials.[3, 4] Compared to other techniques, SKPM is nondestructive and compatible to ambient conditions. Tue, 14 May 2019 10:29:00 +0000 Webinar: Single Cell Injection, Deposition and Aspiration One of the challenges in single cell biology is to address and manipulate single cells locally while being able to monitor their reaction after the manipulation. Mon, 13 May 2019 07:36:00 +0000 Proposing Perfect Material for Lasers Weyl semimetals are a recently discovered class of materials, in which charge carriers behave the way electrons and positrons do in particle accelerators. Researchers from the Moscow Institute of Physics and Technology and Ioffe Institute in St. Petersburg have shown that these materials represent perfect gain media for lasers. Thu, 09 May 2019 11:30:00 +0000 Bessel Beams Enable 3D Microscopy New publication by caesar scientists Andres Flores Valle and Johannes Seelig in Optics Express: A special fanning out of laser beams makes it possible to scan 3D images at high frame rates. Tue, 07 May 2019 05:55:00 +0000 Tracking Small Things in Cells Living cells can react to disturbances with a changed metabolism, but direct observation of trafficking metabolites in live cells is difficult. An international team of scientists has now developed a class of remarkably small fluorophores called SCOTfluors. The dyes emit light in the visible to near-infrared range and can be attached to common metabolites. The study was published in the journal Angewandte Chemie. Mon, 06 May 2019 12:35:00 +0000 3D Printed Digital Holographic Microscope for Medical Diagnostics in Developing Countries Researchers have used 3D printing to make an inexpensive and portable high-resolution microscope that is small and robust enough to use in the field or at the bedside. The high-resolution 3D images provided by the instrument could potentially be used to detect diabetes, sickle cell disease, malaria and other diseases. Tue, 30 Apr 2019 10:33:00 +0000 Ernst-Ruska-Prize 2019 for Dr. Florent Houdellier and Prof. Claus Ropers The German Society for Electron Microscopy (Deutsche Gesellschaft für Elektronenmikroskopie, DGE) awards the internationally renowned Ernst-Ruska-Prize to Dr. Florent Houdellier (CEMES Laboratory, Toulouse, France) and to Prof. Claus Ropers (Georg-August-Universität, Göttingen, Germany) for their outstanding scientific achievements related to electron microscopy. The prize will be awarded at the opening ceremony of the microscopy conference MC2019 in Berlin on September 2nd, 2019. Fri, 26 Apr 2019 11:21:00 +0000 Electron Diffraction Measurements To design and improve energy storage materials, smart devices, and many more technologies, researchers need to understand their hidden structure and chemistry. Advanced research techniques, such as ultra-fast electron diffraction imaging can reveal that information. Now, a group of researchers from the U.S. Thu, 25 Apr 2019 13:29:00 +0000 Contribute to the AFM Event of the Year - NSFE 2019 Share your research with the AFM community of Europe and submit an abstract at the 2nd NanoScientific Forum Europe (NSFE2019) to be held at University of Bologna Sept. 11-13, 2019. Wed, 17 Apr 2019 16:14:00 +0000 Creating Ultrafast 3D Images of Nanostructures Lensless microscopy with X-rays, or coherent diffractive imaging, is a promising approach. It allows researchers to analyse complex three-dimensional structures, which frequently exist in nature, from a dynamic perspective. Whilst two-dimensional images can already be generated quickly and in an efficient manner, creating 3D images still presents a challenge. Generally, three-dimensional images of an object are computed from hundreds of individual images. This takes a significant amount of time, as well as large amounts of data and high radiation values. Wed, 17 Apr 2019 08:35:00 +0000 Label-Free Cell Nuclei Analysis with AI Automated analysis of cell populations in microwell plates, without the need for fluo-rescent labeling, offers researchers a number of significant benefits. For the process to be reliable, however, it is essential that proto-cols are both robust and easy to use. Meth-ods based on artificial intelligence (AI) are ideally suited to address this challenge. Using the right software, AI-based image analysis requires minimal human input and a short training phase. Wed, 17 Apr 2019 06:17:00 +0000 Microscopy in the Body Biotechnologists, physicists, and medical researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have developed technology for microscopic imaging in living organisms. A miniaturised multi-photon microscope, which could be used in an endoscope in future, excites the body’s own molecules to illuminate and enables cells and tissue structures to be imaged without the use of synthetic contrast agents. Tue, 16 Apr 2019 17:45:00 +0000 New Microscopy Technique Peers Deep Into the Brain In order to understand the brain, scientists must be able to see the brain--cell by cell, and moment by moment. However, because brains comprise billions of microscopic moving parts, faithfully recording their activity comes with many challenges. In dense mammalian brains, for example, it is difficult to track rapid cellular changes across multiple brain structures--particularly when those structures are located deep within the brain. Tue, 16 Apr 2019 05:17:00 +0000