Science Overview | Imaging & Microscopy - Research, Development, Production

Jan. 11, 2019
ScienceLight Microscopy
$Defining a New Diffraction Limit$
Defining a New Diffraction Limit
Super-resolution techniques outperform Abbe’s diffraction limit, urging for a new theoretical framework. Prior to the super resolution’s era, Feynman used a more general definition: instead of using the minimum distance to ...
Jan. 02, 2019
ScienceScanning Probe Microscopy
A Window on the Nanoscale
Microscopy typically comes in one of two flavors, providing either structural detail or functional context. Rarely does a microscopy technique bridge the void of form-to-function as well as high-speed-AFM. Augmenting this with nanoscale ...
Nov. 26, 2018
ScienceElectron and Ion Microscopy
Shaping the Electron Wavefronts
The shape and intensity profile of the electron beam are critical in determining the final image quality that can be achieved in (scanning) transmission electron microscopy. Classic imaging theory would have us believe that optimal ...
Nov. 26, 2018
ScienceLight Microscopy
New Light Choice for Virtual Skin Biopsy
Harmonic generation microscopy (HGM) is one of the most important techniques for optical virtual skin biopsy. The occurrence of optical harmonics mainly relies on the interaction between ultrafast laser pulses and the skin tissue. ...
Nov. 26, 2018
ScienceLight Microscopy
Multimodal Microscopy for Tissue Diagnostics
Multimodal nonlinear microscopy using near infrared excitation lasers enables noninvasive, label-free high resolution imaging of native tissue. The methods are highly promising for biomedical applications, e.g., frozen section analysis in ...
Sep. 13, 2018
ScienceLight Microscopy
Label-Free Imaging of Carbon-Based Nanoparticle Pollutants in Biological Settings
Carbon-based nanoparticles are widely produced, both unintentionally like the environmental contaminant black carbon as well as intentionally such as carbon black or carbon nanotubes. Although detrimental environmental and health effects ...
Sep. 12, 2018
ScienceLight Microscopy
Toward Millisecond Volumetric Microscopy
Optical microscopes are the tool-of-choice to study the dynamics of living organisms with subcellular resolution. However, current systems are optimized to acquire two-dimensional information from a single focal plane. While volumetric ...
Sep. 12, 2018
ScienceLight Microscopy
Light Sheet Module for 3D Imaging
A miniaturized fiber-coupled light sheet module has been adapted to an inverted fluorescence microscope. This permits to combine light sheet microscopy with any other kind of imaging, e.g. fluorescence, laser scanning or light scattering ...

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